Effect of Methyl Jasmonate Elicitation on Triterpene Production and Cytotoxic Activity of Ganoderma applanatum Mycelial Culture Extracts
This research explored how treating mushroom cultures with a plant hormone called methyl jasmonate could increase the production of beneficial compounds that may help fight cancer. The scientists grew Ganoderma applanatum mushroom cells in the laboratory and found they could significantly boost the production of therapeutic molecules called triterpenes. These compounds showed promising ability to selectively kill cancer cells while causing minimal harm to normal cells. Impacts on everyday life: – Provides a sustainable way to produce natural anti-cancer compounds – Demonstrates potential for developing new cancer treatments from mushrooms – Offers an environmentally-friendly alternative to harvesting wild mushrooms – Shows promise for more targeted cancer therapies with fewer side effects – Advances our understanding of how to optimize production of medicinal compounds from fungi