Fungal Species: Cunninghamella blakesleeana

Cunninghamella echinulata DSM1905 biofilm-based L-asparaginase production in pneumatically-driven bioreactors

Scientists tested different types of bioreactors to grow a fungus called Cunninghamella echinulata that produces L-asparaginase, an enzyme used to treat leukemia and lymphoma. They found that a special hybrid bioreactor with a mesh scaffold allowed the fungus to form a biofilm, which produced significantly more of the therapeutic enzyme than other reactor types. This discovery could improve the production of cancer-fighting medications.

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Submerged Fermentation of Rhizopus sp. for l-asparaginase Production in Lymphoma Therapy

Researchers developed a new way to produce an anti-cancer enzyme called L-asparaginase using a fungus called Rhizopus, which could offer a safer alternative to current bacterial sources. They designed and tested a special bioreactor system that allows the fungus to grow as a biofilm, significantly increasing enzyme production. The system achieved enzyme activity levels much higher than previous laboratory methods, suggesting it could be scaled up for industrial pharmaceutical production.

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Compatible traits of oleaginous Mucoromycota fungi for lignocellulose-based simultaneous saccharification and fermentation

Researchers tested nine types of fungi to find which ones are best at producing oils from plant waste for making biofuels. They tested how well each fungus could handle higher temperatures and break down cellulose, which is the main component of plant material. Lichtheimia corymbifera was the clear winner because it could grow at higher temperatures while still breaking down plant material efficiently, making it ideal for the combined process of breaking down and fermenting plant waste.

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