Researchers conducted the first comprehensive genetic study of lion’s mane mushrooms (Hericium species) using advanced DNA sequencing techniques. The study resolved long-standing confusion about different species and their relationships, while also describing a new species from western North America. These mushrooms are prized both as food and for traditional medicinal uses, particularly in Asia, and contain compounds with potential anti-inflammatory, antimicrobial, and neuroprotective properties. Better identification of species will help both commercial cultivators and medical researchers work with the correct organisms.