Fungal Species: Cordyceps javanica

Genome Sequence, Comparative Genome Analysis, and Expression Profiling of the Chitinase GH18 Gene Family in Cordyceps javanica Bd01

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Scientists sequenced the complete genome of Cordyceps javanica, a fungus used to control pest insects. They discovered that this fungus has an expanded family of 27 chitinase genes (GH18), which are enzymes that help the fungus penetrate insect exoskeletons. These genes show strong evolutionary conservation and stability, making them valuable for developing more effective natural pesticides and understanding how fungal biocontrol agents work.

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Microsclerotia formation of the biocontrol fungus Cordyceps javanica IF-1106 and evaluation of its stress tolerance and pathogenicity

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Researchers studied a fungus called Cordyceps javanica that can be used to control harmful soil nematodes that damage crop roots. The fungus produces special dormant structures called microsclerotia that can survive extreme heat and UV radiation for extended periods. These microsclerotia showed excellent effectiveness at controlling root-knot nematodes on cucumber plants while also promoting plant growth, making them a promising natural alternative to chemical pesticides.

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Telomere-to-Telomere Assembly of the Cordyceps militaris CH1 Genome and Integrated Transcriptomic and Metabolomic Analyses Provide New Insights into Cordycepin Biosynthesis Under Light Stress

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Researchers successfully sequenced the complete genome of Cordyceps militaris CH1, a medicinal fungus used in traditional Chinese medicine. By exposing the fungus to light and analyzing gene expression and metabolite changes, they discovered that light stress activates key genes involved in producing cordycepin, the main active medicinal compound. This breakthrough provides a foundation for improving cordycepin production in artificial cultivation, making this valuable medicine more affordable and accessible.

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Chemical clues to infection: A pilot study on the differential secondary metabolite production during the life cycle of selected Cordyceps species

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This study examined two types of parasitic fungi (Cordyceps javanica and Cordyceps blackwelliae) that infect insects, comparing how they kill their hosts and what chemical compounds they produce during infection. Researchers found that each species uses different toxic molecules to infect insects, with C. javanica being more deadly and producing diverse compounds called beauveriolides. By analyzing infected insect corpses, scientists provided the first direct evidence that these toxic compounds are actually made during real infections, not just in laboratory cultures.

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Development of Mycoinsecticides: Advances in Formulation, Regulatory Challenges and Market Trends for Entomopathogenic Fungi

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This review explores fungal-based insecticides as environmentally friendly alternatives to chemical pest control. These products use naturally occurring fungi that infect and kill insects through direct contact, making them effective against many crop pests. The review covers different formulation types, product development challenges, and regulatory approval processes in major markets worldwide.

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Advances in submerged liquid fermentation and formulation of entomopathogenic fungi

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This paper reviews how scientists are improving the production of natural fungal pesticides that kill insect pests. Instead of growing fungi on grains in bags, researchers are using large fermentation tanks similar to those used in food and beverage production. These tanks can produce beneficial fungal cells more quickly and efficiently, with better quality control and safety. The paper discusses different types of fungal cells produced, how to make them stable for storage and field use, and how this technology could replace older production methods worldwide.

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