This research evaluated the safety of Lion’s mane mushroom extract through comprehensive toxicology testing. The studies found no harmful effects even at high doses, supporting its safe use in food and supplements. Impact on everyday life: • Confirms the safety of Lion’s mane mushroom supplements for consumer use • Supports the development of new mushroom-based food products • Provides scientific backing for traditional uses of medicinal mushrooms • Helps establish safe dosage guidelines for supplement manufacturers • Gives consumers confidence in using Lion’s mane products