Fungal Species: Auricularia auricula

Optimization of triterpenoids biosynthesis in Athelia termitophila as a source of natural products

Researchers optimized growing conditions for a fungus found in termite nests to dramatically increase production of triterpenoids, naturally-occurring compounds with potent health benefits. Using statistical methods to test different nutrients and conditions, they nearly doubled triterpenoid production and mycelial biomass. These findings could make triterpenoid-based medicines and supplements more affordable and widely available by improving natural production methods.

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Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

This research studied five types of oyster mushrooms grown in Thailand at different stages of maturity. Researchers found that the nutritional content and beneficial compounds in mushrooms change as they grow. Young and middle-stage mushrooms had the highest levels of compounds that fight disease and help manage blood sugar, while fully mature mushrooms had more total nutrients. This information helps farmers decide when to harvest mushrooms based on whether customers want maximum nutrition or maximum health-promoting properties.

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Toxicity of Volatile Organic Compounds Produced by Pathogens Ewingella americana and Cedecea neteri Associated with Pleurotus pulmonarius

Researchers discovered that two types of bacteria (Ewingella americana and Cedecea neteri) causing diseases in oyster mushrooms (Pleurotus pulmonarius) produce harmful volatile compounds. These airborne toxins, especially one called 2,4-di-tert-butylphenol, can damage mushroom tissue and stop mushroom growth at very low concentrations. This is the first study showing that these bacterial volatiles are important factors in mushroom disease, which could help farmers develop better ways to detect and prevent these infections.

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Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice

Researchers created special tablets from two edible mushrooms (yellow oyster mushroom and lion’s mane) enriched with trace elements (chromium, zinc, germanium) to treat diabetes in mice. After three weeks of treatment, the high-dose tablets reduced blood sugar levels by 29%, improved cholesterol levels, boosted the body’s natural antioxidant defenses, and shifted the gut bacteria toward beneficial types that support metabolic health. These results suggest that mushroom-based treatments could potentially offer a natural way to help manage diabetes.

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Three-phase extraction of polysaccharide from Stropharia rugosoannulata: Process optimization, structural characterization and bioactivities

Researchers developed an efficient new method called three-phase extraction to isolate beneficial compounds called polysaccharides from wine cap mushrooms (Stropharia rugosoannulata). These polysaccharides showed strong antioxidant properties and boosted immune cell activity in laboratory tests by triggering specific cellular pathways. The findings suggest these mushroom extracts could become useful ingredients in functional foods or medicines to support immune health.

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Corrigendum: Compounds purified from edible fungi fight against chronic inflammation through oxidative stress regulation

This article is a correction to a previous study about beneficial compounds found in edible mushrooms. The study examined how various mushroom-derived substances like polysaccharides and peptides can combat chronic inflammation by reducing oxidative stress in the body. Multiple mushroom species were analyzed for their antioxidant properties and mechanisms of action. The corrections ensure proper citation of the original research sources while maintaining the core scientific findings.

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Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

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Transcriptome Analysis Reveals Critical Genes Involved in the Response of Stropharia rugosoannulata to High Temperature and Drought Stress

This study examined how a type of edible mushroom called Stropharia rugosoannulata responds to high heat and dry conditions by analyzing which genes become active. Researchers found that under stress, the mushroom activates specific genes that help it survive, particularly through a cellular communication pathway called MAPK. They identified 15 key genes that could be useful for breeding mushroom varieties that better withstand harsh growing conditions, which could improve mushroom farming efficiency.

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Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans

This research discovered that compounds from the edible mushroom Auricularia auricula can help prevent obesity by promoting beneficial gut bacteria. The study found that polysaccharides from this mushroom specifically increase a helpful bacteria called Papillibacter cinnamivorans, which helps reduce weight gain and improve metabolism. Impacts on everyday life: • Provides evidence that eating certain mushrooms may help with weight management • Identifies a new probiotic bacteria that could be developed into weight loss supplements • Demonstrates how dietary choices can positively influence gut bacteria • Offers potential new natural approaches for treating obesity • Suggests mushroom extracts could be developed into prebiotic supplements

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Bioactivities and Health Benefits of Mushrooms Mainly from China

This research reviews how various mushrooms, particularly those from China, can benefit human health through their natural compounds and properties. Mushrooms are shown to help fight diseases and promote wellness in multiple ways. Impacts on everyday life: • Mushrooms can be incorporated into daily diet as a natural way to boost immune system and prevent chronic diseases • Certain mushroom species could help in managing conditions like diabetes and high cholesterol • Mushroom extracts and compounds could provide natural alternatives to synthetic medicines • Regular consumption of medicinal mushrooms may help prevent cancer and other serious illnesses • Mushrooms offer a sustainable and natural source of health-promoting compounds

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