This research provides a comprehensive overview of specialized chemical compounds called sesquiterpenoids that are produced by fungi. These compounds are important because they can potentially be developed into new medicines. The research impacts everyday life in several ways: • New drug development: Many of these compounds show promise for developing new antibiotics, anti-cancer drugs, and anti-inflammatory medications • Food safety: Understanding fungal toxins helps protect our food supply • Agricultural applications: Some compounds could be used to develop new crop protection products • Industrial applications: These compounds could lead to new natural preservatives or antimicrobial agents • Environmental protection: Better understanding of fungal chemistry helps in developing eco-friendly pest control methods