Fungal Species:  Aspergillus sojae

Activation of Secondary Metabolism and Protease Activity Mechanisms in the Black Koji Mold Aspergillus luchuensis through Coculture with Animal Cells

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Researchers found that growing koji mold (Aspergillus luchuensis) alongside mouse immune cells in the laboratory significantly increases the production of valuable bioactive compounds. The mold releases enzymes called proteases that break down proteins from the animal cells, which the fungus then uses as building blocks to create medicinal compounds. This discovery shows that coculturing microorganisms with animal cells is an effective strategy to unlock hidden chemical production capabilities in fungi, which could lead to new medicines and useful compounds.

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Edible mycelium as proliferation and differentiation support for anchorage-dependent animal cells in cultivated meat production

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Scientists developed a new technology using edible mushroom mycelium (the root-like structure of fungi) as a scaffold to grow animal muscle cells for cultivated meat production. They tested different fungal species and found that mycelium from koji mold (Aspergillus oryzae) worked best for supporting cell growth and maturation. Unlike current plastic microcarriers that must be removed from the final product, these edible carriers can be incorporated directly into the meat, adding nutritional value and reducing waste.

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Filamentous fungal pellets as versatile platforms for cell immobilization: developments to date and future perspectives

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Filamentous fungi, commonly known as molds, can be grown into small spherical structures called pellets that act as excellent platforms for attaching and growing various types of cells. These fungal pellets are sustainable, biodegradable alternatives to synthetic materials and can support different cell types for applications ranging from producing cultivated meat to treating wastewater. The porous structure of fungal pellets allows cells to attach and grow while maintaining the ability to transfer nutrients and oxygen efficiently.

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Taxonomy of Aspergillus Section Flavi and their Production of Aflatoxins, Ochratoxins and Other Mycotoxins

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This research provides an updated classification system for an important group of fungi that can contaminate food with dangerous toxins. The study discovered several new fungal species and mapped out which species produce which toxins. This knowledge is crucial for food safety and public health. Impacts on everyday life: – Better understanding of which fungi pose risks to food safety – Improved methods for identifying dangerous fungal contaminants in foods – More accurate testing of foods for potential toxin contamination – Enhanced ability to prevent fungal spoilage in food production – Better protection of public health through improved food safety measures

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