Fungal Species:  Armillaria mellea

The Effect of Mushroom Culture Filtrates on the Inhibition of Mycotoxins Produced by Aspergillus flavus and Aspergillus carbonarius

Researchers tested extracts from 42 different mushroom species to find ones that could prevent harmful toxins produced by mold from contaminating our food and animal feed. They discovered that two mushroom species—turkey tail mushroom and a species called Schizophyllum commune—produced compounds that blocked over 90% of toxin production. These mushroom compounds work by boosting the mold’s natural defense systems, essentially making it unable to produce the dangerous toxins.

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Ergothioneine: An Antioxidative, Neuroprotective and Anti-Inflammatory Compound from Mushroom Residuals

Ergothioneine is a powerful antioxidant found mainly in mushrooms that protects brain health and reduces inflammation. Mushroom processing creates large amounts of waste like stems and leftover substrate that actually contain high levels of this beneficial compound. Scientists have developed sustainable methods to extract ergothioneine from this waste, creating opportunities for new health supplements and functional foods while reducing waste and supporting environmental sustainability.

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Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles

Periodontitis is a serious gum disease that causes tooth loss and affects overall health. This review examines how polysaccharides (complex carbohydrates) from plants and fungi can help treat periodontitis by reducing inflammation, fighting bacteria, and helping gum tissue repair. These natural compounds work through multiple biological pathways to improve oral health outcomes while avoiding the side effects and resistance problems associated with conventional drugs.

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Fungal symbiont Mycena complements impaired nitrogen utilization in Gastrodia elata and supplies indole-3-acetic acid to facilitate its seed germination

A special type of orchid called Gastrodia elata cannot survive on its own because it has lost the ability to produce its own food and certain plant growth hormones. Instead, it relies completely on a fungal partner called Mycena to provide nitrogen nutrients and auxin (a growth hormone). This study reveals exactly how Mycena does this by analyzing their genes and how they communicate, showing that the fungus acts as a nutritional life-support system for the orchid seed’s germination.

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Evolutionary Dynamics and Functional Bifurcation of the C2H2 Gene Family in Basidiomycota

Researchers analyzed genetic instructions for zinc finger proteins across 30 species of basidiomycete fungi (including mushrooms and fungal pathogens). They found that different fungal species evolved different versions of these proteins based on their lifestyle: fungi that break down wood kept complex gene versions with lots of regulatory switches, while parasitic fungi streamlined their genes for efficiency. By studying when and where these genes are active during mushroom development, scientists discovered they orchestrate different stages from cold adaptation to mature fruiting body formation, revealing how fungi adapt to diverse ecological roles.

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Towards engineering agaricomycete fungi for terpenoid production

Mushroom-forming fungi, particularly species like shiitake and oyster mushrooms, naturally produce valuable compounds called terpenoids used in medicines, food, and cosmetics. Scientists are learning to genetically engineer these fungi to produce even larger amounts of these beneficial compounds, potentially making them as important to biotechnology as baker’s yeast and mold have been historically. This could create new sustainable sources for medicinal compounds and industrial chemicals.

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Hierarchical Structure of the Program Used by Filamentous Fungi to Navigate in Confining Microenvironments

This research reveals how fungi navigate through tight spaces like soil and wood using sophisticated biological ‘programs’ operating at three levels: individual fungal threads, groups of threads, and entire fungal networks. Each level uses different strategies like sensing openings, remembering directions, and avoiding neighbors to efficiently explore confined spaces. By understanding these natural algorithms, scientists could develop new bio-inspired solutions for navigation and space exploration problems.

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Neutral Polysaccharides From Hohenbuehelia serotina With Hypoglycemic Effects in a Type 2 Diabetic Mouse Model

Researchers extracted and studied special compounds called polysaccharides from H. serotina mushrooms. They found that these compounds significantly reduced blood sugar levels in mice with type 2 diabetes and also protected the liver. The study shows that mushroom polysaccharides could be a safe, natural alternative to existing diabetes medications with fewer side effects.

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