This research addresses a critical problem in measuring silver content in certain mushrooms, particularly silver-accumulating Amanita species. Scientists discovered that standard laboratory digestion procedures using nitric acid can cause silver to precipitate as silver chloride, making it invisible to measurement instruments and leading to false low results. The study demonstrates that neutron activation analysis is more accurate for measuring silver in these mushrooms, or alternatively, specialized multi-step digestion procedures can dissolve the precipitated silver chloride to obtain accurate measurements.