Fungal Species: Amanita bisporigera

Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

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First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds

Researchers studied a Korean edible mushroom called Amanita hemibapha subsp. javanica and found it contains compounds that can kill the bacteria Helicobacter pylori, which causes stomach ulcers and gastric cancer. One compound in particular showed strong antibacterial activity, performing even better than some known antibiotics. These findings suggest this mushroom could be a natural source for developing new medicines to treat H. pylori infections and fight antibiotic-resistant strains.

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