This research examined how different levels of cadmium (a toxic heavy metal) affect two strains of the medicinal mushroom Agaricus brasiliensis. The study found important differences in how these mushroom strains handle cadmium contamination, with one strain (J77) showing better resistance to cadmium while maintaining lower absorption levels. This has important implications for safer mushroom cultivation and consumption. Impacts on everyday life: – Helps identify safer mushroom varieties for consumption with lower heavy metal accumulation – Provides guidance for mushroom growers on selecting better strains for contaminated environments – Contributes to improving food safety standards for edible mushrooms – Helps understand how to maintain nutritional quality of mushrooms under environmental stress – Offers insights for developing more resistant mushroom strains for future cultivation