Agaricus blazei Murill

The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

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This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

A Review of Novel Antioxidant Ergothioneine: Biosynthesis Pathways, Production, Function and Food Applications

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Ergothioneine is a powerful natural antioxidant found mainly in mushrooms that protects cells from damage and may help prevent diseases like Alzheimer’s and heart disease. Currently, producing ergothioneine from mushrooms is expensive and slow, but scientists have developed faster fermentation methods using engineered microbes that could make it cheaper and more available. This compound can be added to foods and supplements to boost health benefits, and researchers are exploring its use beyond seafood to other food products like meat and baked goods.

Research progress of edible mushroom polysaccharide-metal trace element complexes

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This research reviews how edible mushroom polysaccharides can be combined with essential metals like iron, selenium, and zinc to create health-boosting supplements. These complexes improve how our bodies absorb and use these important minerals, offering benefits like better immune function, antioxidant protection, and potential cancer-fighting properties. Scientists are studying different ways to make these complexes and testing their effectiveness for treating various health conditions.

Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

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This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

LeLISA: A New Lectin-Based Immunoassay for Evaluation of Mucinous and Serous Content in Pancreatic Cystic Neoplasms

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Researchers developed a new laboratory test called LeLISA that uses special proteins called lectins to distinguish between different types of pancreatic cysts. By testing cyst fluid samples against eight different lectins, they found that dangerous mucinous cysts showed strong binding patterns while safer serous cysts showed much weaker signals. This test could help doctors identify which pancreatic cysts need surgery and which ones are safe to monitor over time.

Critical review on chemical compositions and health-promoting effects of mushroom Agaricus blazei Murill

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Agaricus blazei Murill is an edible mushroom that contains many beneficial compounds including polysaccharides, vitamins, and minerals. Research shows it may help boost the immune system, reduce blood sugar levels, protect the liver, fight inflammation, and even have anti-cancer properties. While animal studies show promising results, more human clinical trials are needed to confirm its health benefits and establish proper dosing for therapeutic use.

The Mushroom Agaricus Blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation Through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation

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This research examines how the medicinal mushroom Agaricus blazei Murill (AbM) can help fight various diseases by boosting and balancing the immune system. The mushroom contains natural compounds that stimulate immune cells to better fight cancer, infections, and reduce allergic reactions and inflammation. Impact on everyday life: • Could provide a natural supplement to help prevent and treat various diseases • May help reduce allergy symptoms and inflammation without serious side effects • Shows potential as complementary treatment alongside conventional cancer therapies • Offers a safe way to enhance the body’s natural immune defenses • Could help reduce dependence on conventional anti-inflammatory medications

Immunomodulating Compounds in Basidiomycetes: A Review of Polysaccharides and Their Immune Effects

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This research examines how certain compounds found in mushrooms can boost our immune system and fight cancer. Scientists have discovered that specific sugar molecules called β-glucans, found in mushrooms like shiitake and blazei, can help strengthen our body’s natural defense mechanisms. This has important implications for human health and medicine. Impacts on everyday life: • Provides scientific support for including medicinal mushrooms in daily diet for immune health • Offers natural alternatives for cancer prevention and treatment • Helps explain why traditional Asian medicine has long valued certain mushrooms • Suggests new ways to develop natural medicines with fewer side effects • Shows potential for developing new supplements for immune system support

Medicinal and Edible Fungi as an Alternative Medicine for Treating Age-Related Disease

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This research examines how certain medicinal mushrooms can be used to treat various age-related diseases. Traditional mushrooms like Cordyceps, Agaricus, and Ganoderma have shown promising results in treating conditions like diabetes, cancer, and heart disease. These fungi contain natural compounds that can help reduce inflammation, boost immunity, and protect against cellular damage. Impacts on everyday life: • Provides natural alternatives to conventional medications for age-related conditions • Offers potential dietary supplements for disease prevention • Demonstrates the value of traditional medicine in modern healthcare • Suggests new ways to maintain health during aging • Shows how common mushrooms can have powerful health benefits

Can Medicinal Mushrooms Have Prophylactic or Therapeutic Effect Against COVID-19 and its Pneumonic Superinfection and Complicating Inflammation?

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This research examines how certain medicinal mushrooms might help fight COVID-19 infection and its complications. These mushrooms have shown ability to boost immune function, fight infections, and reduce harmful inflammation. The study suggests they could potentially help protect against or treat COVID-19 in several ways: • Could help prevent or fight secondary bacterial infections that often complicate COVID-19 cases • May help control the excessive inflammation that causes severe COVID-19 symptoms • Could boost the immune system’s ability to fight the virus • Might help protect against antibiotic-resistant bacteria • Could potentially be used as a natural supplement alongside other COVID-19 treatments

Fungal Species: Agaricus blazei Murill