Acremonium multiramosum

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

mycolabadmin

Researchers discovered five potent anti-cancer compounds from Arctic fungi called Acremonium strains. Using advanced chemical analysis techniques, they identified and tested these cyclic depsipeptides against various cancer cell types. The most active compound showed promising results against breast cancer and melanoma cells with extremely low concentrations needed for effect. These findings suggest Arctic microorganisms could be valuable sources for developing new cancer treatments.

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

mycolabadmin

Researchers studied fungi collected from Arctic driftwood to find new cancer-fighting compounds. Using advanced chemical analysis tools, they identified six different fungal strains and found that one strain, Acremonium synnematoferum, produced five unique compounds called depsipeptides. These compounds killed cancer cells in laboratory tests, showing promise as potential cancer treatments. This research highlights how extreme Arctic environments can harbor fungi with powerful medicinal properties.

Fungal Species: Acremonium multiramosum

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides