This research examined an edible mushroom found in Thailand called Boletus griseipurpureus, studying both its genetic makeup and potential medical benefits. The study found that extracts from this mushroom can effectively fight against harmful bacteria, including antibiotic-resistant strains. This discovery is particularly significant for public health and natural medicine development. Impacts on everyday life: • Identifies a natural food source with potential antibacterial properties • Suggests new possibilities for developing natural antibiotics from mushrooms • Contributes to our understanding of safe, edible wild mushrooms • Opens new avenues for natural health supplements • Provides scientific validation for traditional uses of mushrooms in medicine