Research Keyword: Viral inhibition

Quest for Anti-SARS-CoV-2 antiviral therapeutics: in-silico and in-vitro analysis of edible mushroom- Cordyceps militaris

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Researchers tested an edible mushroom called Cordyceps militaris to see if it could fight SARS-CoV-2, the virus that causes COVID-19. Using computer modeling and laboratory experiments, they found that a compound in the mushroom called cordycepin strongly attached to the virus’s spike protein and reduced viral numbers by about 50% in cell cultures. The study supports traditional uses of this mushroom and suggests it could be helpful in managing COVID-19 as the disease becomes endemic.

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Anti-Influenza Activity of Medicinal Material Extracts from Qinghai–Tibet Plateau

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Researchers tested extracts from traditional Tibetan medicinal plants, mushrooms, and lichens to see if they could fight influenza virus. They found that seven out of nine extracts could reduce influenza virus infection in laboratory cells, with a mushroom extract called Armillaria luteo-virens showing particularly strong antiviral effects. These results suggest that traditional medicinal materials from the Qinghai–Tibetan plateau could be valuable sources for developing new flu treatments that might work better against drug-resistant flu strains.

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