UPLC-MS/MS – mycolab.ai

Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

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This study examines how different drying methods affect the lipid content of Cordyceps sinensis, a valuable medicinal mushroom. Researchers compared three drying techniques—freeze-drying, oven-drying, and air-drying—and found that freeze-drying best preserves the mushroom’s beneficial lipids, while oven-drying causes significant degradation. The findings provide practical guidance for mushroom producers on selecting optimal drying methods to maintain the medicinal quality and nutritional value of this prized fungus.

Honeybee associated Aspergillus niger AW17 as a source of selective anticancer compounds with cytotoxicity evaluation in human cancer cell lines

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Scientists discovered that a fungus found in honeybees can produce compounds that effectively kill cancer cells while leaving healthy cells largely unharmed. The fungus (Aspergillus niger AW17) contains unique bioactive compounds including high levels of oleic acid and a rare compound called pachymic acid. When tested against four types of human cancer cells, the fungal extract was particularly effective against liver and colorectal cancer. This finding suggests that exploring specialized environments like beehives could lead to new cancer treatments with fewer side effects.

Effect of Different Drying Methods on the Quality and Nonvolatile Flavor Components of Oudemansiella raphanipes

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This study compared seven different methods for drying a medicinal mushroom called O. raphanipes to determine which best preserves its flavor and nutrients. Researchers found that freeze-drying and ultrasound-assisted hot air drying at lower temperatures were most effective at maintaining the mushroom’s taste-enhancing compounds and appearance. The findings provide practical guidance for commercial production of this nutritious mushroom.

Mushrooms Do Produce Flavonoids: Metabolite Profiling and Transcriptome Analysis of Flavonoid Synthesis in the Medicinal Mushroom Sanghuangporus baumii

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Researchers discovered that the medicinal mushroom Sanghuangporus baumii produces 81 different flavonoids, compounds known for their health benefits including antioxidant and anti-cancer properties. Using advanced genetic and chemical analysis, they identified the genes and processes responsible for this flavonoid production in mushrooms, which differs from how plants make these compounds. By increasing the activity of a key gene called PAL, they were able to boost flavonoid production in the mushroom. This discovery opens new possibilities for using mushrooms as biological factories to produce flavonoids for medical and nutritional applications.

Research Keyword: UPLC-MS/MS

Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

Honeybee associated Aspergillus niger AW17 as a source of selective anticancer compounds with cytotoxicity evaluation in human cancer cell lines

Effect of Different Drying Methods on the Quality and Nonvolatile Flavor Components of Oudemansiella raphanipes

Mushrooms Do Produce Flavonoids: Metabolite Profiling and Transcriptome Analysis of Flavonoid Synthesis in the Medicinal Mushroom Sanghuangporus baumii