Research Keyword: UHPLC-MS/MS

From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

mycolabadmin

Researchers studied a medicinal mushroom called Ganoderma lucidum to identify compounds that could fight cancer. They found nine rare compounds called depsidones that showed promise against different types of cancer cells, including liver, colon, breast, and lung cancer. The compounds were shown to work by binding to cancer-related proteins, suggesting they could be developed into new cancer treatments.

Read More »

Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids

mycolabadmin

Scientists analyzed 226 mushroom samples from about 30 psychotropic species to measure their psilocybin and related compound content. They found that the amounts of these compounds vary greatly, even within the same species, making it difficult to predict how strong a mushroom will be. The research shows that Psilocybe species generally contain the most psychoactive compounds, with some varieties containing over 15 times more psilocybin than others, highlighting safety concerns for users.

Read More »

Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

mycolabadmin

This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

Read More »

Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of Cytospora mali in “Jin Hong” branches

mycolabadmin

This research examined how apple trees defend themselves against a serious fungal disease called Valsa canker caused by Cytospora mali. Scientists used advanced genetic and chemical analysis techniques to identify which genes and protective compounds are activated when apple branches are infected. They found that healthy apple trees fight the infection by strengthening their cell walls, producing special protective enzymes, and accumulating defense chemicals like α-linolenic acid and betaine. These discoveries could help develop better ways to prevent or manage this destructive disease in apple orchards.

Read More »

Determination of Tryptamine Alkaloids and Their Stability in Psychotropic Mushrooms

mycolabadmin

Researchers analyzed the active compounds found in psychotropic mushrooms used for therapy and microdosing. They found that the amounts of these compounds vary greatly between mushroom samples and can degrade during storage. Fresh mushrooms stored in freezers degraded faster than dried mushrooms kept at room temperature in the dark, suggesting proper storage is important for maintaining therapeutic effectiveness.

Read More »
Scroll to Top