Research Keyword: type I hypersensitivity

Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

Scientists studied two fungi that infect plants to see if they could cause asthma-like reactions in mice. They found that these fungi triggered inflammatory responses and produced antibodies similar to other known allergens. While not as potent as ovalbumin (a common test allergen), these plant-infecting fungi showed potential as respiratory allergens that may affect people exposed to them.

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Chronic Urticaria Suspected to be Caused by a 13.5 mg Levonorgestrel Intrauterine Device (Skyla®)

A woman developed a chronic hive-like rash that lasted for two years after having a hormone-releasing intrauterine device (Skyla®) implanted. Extensive medical testing ruled out common causes like vitamin D deficiency and allergies. When the device was removed, the rash gradually disappeared completely over two years. This case suggests that the progesterone released from the device may have triggered an allergic reaction in this particular patient.

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