Research Keyword: tryptamine compounds

Norpsilocin: freebase and fumarate salt

Researchers determined the crystal structures of norpsilocin, a naturally occurring compound found in magic mushrooms that is chemically similar to psilocin. This work is important because norpsilocin appears to be as potent as psilocin at serotonin receptors and may contribute to the therapeutic effects of magic mushroom extracts. By obtaining pure crystalline forms and understanding the compound’s structure, scientists can better study its properties and potential medical applications for treating conditions like depression and anxiety.

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Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives

This review examined research on Psilocybe mushrooms and their chemical compounds, particularly psilocybin and psilocin, which show promise for treating depression and anxiety. The authors found that while these psychoactive compounds have been extensively studied, many other chemical substances in these mushrooms remain unexplored. Additionally, preliminary studies suggest these mushrooms may have antimicrobial and antioxidant properties, though more research is needed. The review highlights significant gaps in understanding the full potential of Psilocybe mushrooms for medical applications.

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