Research Keyword: treatment guidelines

Informing the World Health Organization Fungal Priority Pathogens List (WHO-FPPL): A collection of systematic reviews

The World Health Organization created a priority list of dangerous fungal infections affecting millions of people globally each year. Experts reviewed 19 different fungal pathogens and ranked them by how dangerous they are and how much they need research and treatment development. The list identifies which fungal infections should get the most attention from doctors, researchers, and public health officials to improve patient outcomes and reduce deaths.

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Prevalence of Candida and Other Yeasts in Vulvovaginal Infections during Pregnancy: A 10-Year Serbian Survey

This 10-year study from Serbia examined vaginal yeast infections in nearly 2,200 pregnant women. Researchers found that yeast infections occurred in about 48% of symptomatic pregnant women, with Candida albicans being the most common cause. Importantly, the study discovered that other yeast species are increasingly important in these infections, and new identification methods (MALDI-TOF MS) revealed these species are often misidentified by traditional laboratory methods. The findings suggest that accurate yeast identification is essential for choosing the right treatment during pregnancy.

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Antifungal Policy and Practice Across Five Countries: A Qualitative Review

This study examines how well five different countries handle invasive fungal infections through their healthcare policies and systems. Researchers found that while these infections affect millions of people globally, most countries lack comprehensive policies to diagnose, treat, and manage them effectively. Major issues include inadequate healthcare provider training, limited access to rapid diagnostic tests, and insufficient antifungal medications in some regions. The study recommends that countries develop better national strategies for preventing, diagnosing, and treating these serious infections.

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ESCMID-EFISG Survey on Diagnostic and Therapeutic Capacity for Invasive Fungal Infections in Belgium, the Netherlands, and Luxembourg: A Focus on High Azole Resistance

This survey examined how well hospitals in Belgium, the Netherlands, and Luxembourg can diagnose and treat serious fungal infections, especially in patients whose immune systems are weakened. The researchers found that while most hospitals have good access to testing and antifungal medications, some important tests are still missing, and many hospitals send samples to other facilities for testing, which can delay treatment. Since this region has unusually high rates of fungal infections that resist common antifungal drugs, improving access to advanced diagnostic tests is crucial for patient survival.

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