This research shows that button mushrooms (Agaricus bisporus) can absorb and accumulate harmful cadmium from contaminated soil. When exposed to cadmium stress, the mushrooms increase their protective chemical defenses, including antioxidant enzymes and organic acids, to survive the toxic conditions. The study demonstrates that these edible mushrooms could potentially be used as a practical and cost-effective method to clean up cadmium-polluted soils.