transcriptomics – Page 7

The dark side of avocados: a review of anthracnose and stem-end rot in postharvest fruit

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Avocados are a valuable global fruit crop, but two fungal diseases—anthracnose and stem-end rot—cause major economic losses by making fruit unmarketable. These fungi infect avocados in the orchard but remain hidden until the fruit ripens, making them difficult to detect and control. Recent advances in detection technology and disease management strategies, including biological controls and natural treatments, offer promising solutions to reduce losses and keep avocados fresh from farm to table.

Molecular characterization of four novel mycoviruses in entomopathogenic and nematophagous fungi

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Scientists discovered four new types of viruses that infect specific fungi used for pest control. These fungi naturally kill insects and parasitic worms, making them valuable alternatives to chemical pesticides. Understanding the viruses in these beneficial fungi could help improve their effectiveness as biological control agents and reveal new ecological relationships.

Revealing the metabolic potential and environmental adaptation of nematophagous fungus, Purpureocillium lilacinum, derived from hadal sediment

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Scientists discovered a special fungus living in the deepest part of the ocean (Mariana Trench) that can survive extreme pressure and produce compounds with disease-fighting properties. This fungus, Purpureocillium lilacinum, showed promise against bacteria, cancer cells, and parasitic worms. The research revealed how this fungus adapts to survive in one of Earth’s most extreme environments, potentially opening new sources for developing medicines and biological pest control.

Multi-omics Analysis of Experimentally Evolved Candida auris Isolates Reveals Modulation of Sterols, Sphingolipids, and Oxidative Stress in Acquired Amphotericin B Resistance

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Researchers studied how the fungus Candida auris develops resistance to amphotericin B, an important antifungal drug. By evolving two laboratory strains of this fungus under drug pressure, they discovered two different ways the fungus can become resistant: one through stress management genes, the other through changes in its protective lipids. These findings help explain why some clinical infections with this dangerous fungus are so hard to treat.

Analysis of the chitin synthase gene family in Ganoderma lucidum: its structure, phylogeny, and expression patterns

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Scientists studied eight chitin synthase genes in Ganoderma lucidum (reishi mushroom), which are important for building the fungal cell wall and controlling growth. They found that different genes are active at different stages of mushroom development and that six of these genes become more active when exposed to high temperatures, suggesting they help the mushroom survive heat stress. This research helps us understand how mushrooms grow and develop, which could lead to better cultivation methods.

Selection of reliable reference genes in Colletotrichum scovillei during different growth stages, host interactions, and plant extract treatment for qRT-PCR

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This research identifies the best internal control genes to use when measuring gene activity in a fungus that causes pepper disease. Scientists tested eight different reference genes under various conditions like fungal growth and pepper infection, plus when treating the fungus with plant extracts. Different genes worked best for different situations: one gene was best during fungal growth, another during infection, and a third when treated with plant extracts. These findings will help future studies better understand how this disease-causing fungus works and develop better control methods.

Improving the production of micafungin precursor FR901379 in Coleophoma empetri using heavy-ion irradiation and its mechanism analysis

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Scientists successfully improved the production of a key ingredient for the antifungal drug micafungin by using heavy-ion radiation to create improved strains of a fungus called Coleophoma empetri. The best mutant strain produced over 250% more of the desired compound than the original strain. By analyzing the genetic changes in these improved strains, researchers identified specific genes related to fungal structure and metabolism that contribute to higher production, providing insights for future improvements to the manufacturing process.

Fusarium pseudonygamai Promotes Blastospore Transformation in Ophiocordyceps sinensis: Insights into Microbial Interaction and Key Mechanisms

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This study reveals how a beneficial microorganism (Fusarium pseudonygamai) helps the medicinal fungus Chinese cordyceps transform and grow properly. The microorganism produces a natural sugar-like substance called mannitol that signals the fungus to change from spore form into thread-like hyphae. By understanding this microbial communication, scientists can potentially improve the artificial production of Chinese cordyceps, reducing pressure on wild populations.

Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

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This study explains why morel mushroom strains weaken when repeatedly grown in laboratories. Researchers found that degenerated strains lose the ability to produce protective compounds called flavonoids, which act as natural antioxidants. By understanding these molecular changes, the researchers suggest that avoiding frequent subculturing and using preservation methods like low-temperature storage could help keep morel strains healthy and productive.

Biology and Application of Chaetomium globosum as a Biocontrol Agent: Current Status and Future Prospects

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Chaetomium globosum is a fungus that can protect crops from various plant diseases by producing toxic compounds and parasitizing harmful pathogens. It also helps plants defend themselves naturally and improves soil health by promoting beneficial microorganisms. This makes it a promising alternative to chemical pesticides for sustainable farming, though more research is needed to optimize its effectiveness in real field conditions.

Research Keyword: transcriptomics