Research Keyword: tolerability

Safety, feasibility, and tolerability of psilocybin in older adults with amnestic MCI: Preliminary data from a SV2a PET imaging study

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Researchers investigated whether psilocybin, a compound from certain mushrooms, could be safely used to treat memory problems in older adults with mild cognitive impairment. In this early-stage study, participants received either psilocybin or a placebo while researchers used brain imaging to measure changes in synaptic connections. The preliminary results suggest psilocybin was well-tolerated with manageable side effects like dizziness, and participants were able to complete the study without serious problems.

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Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial

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This study tests whether psilocybin (a psychedelic compound) combined with intensive therapy can help treat chronic PTSD better than therapy alone. Fifteen patients with PTSD will receive one dose of psilocybin alongside 12 therapy sessions completed over a single week. Researchers will track feasibility, safety, symptom improvements, and use wearable devices to monitor physiological changes. The results will help determine whether larger trials should test this innovative combination therapy.

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Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review

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Coriolus versicolor, also known as turkey tail mushroom, has been used in traditional Chinese medicine for thousands of years. Recent scientific research shows it may help fight breast cancer through multiple mechanisms: killing cancer cells directly through programmed cell death pathways, breaking down the estrogen that fuels some breast cancers, preventing cancer spread, and boosting the immune system. While early studies are promising and one clinical trial showed good safety and immune benefits, larger studies are needed before this mushroom can be recommended as an official cancer treatment.

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