Research Keyword: tissue imaging

Lectins as versatile tools to explore cellular glycosylation

Lectins are natural proteins that selectively bind to sugars on cell surfaces, discovered over 130 years ago as tools for studying cell chemistry. They have become especially valuable in cancer research, revealing how cancer cells have abnormal sugar patterns that predict how aggressively they spread. Modern biotechnology now allows scientists to create enhanced lectin versions and use them in high-throughput screening to discover new disease markers and improve patient diagnosis.

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Accelerated protein retention expansion microscopy using microwave radiation

Scientists have developed a faster way to examine brain tissue at extremely small scales using a combination of expansion microscopy and microwave radiation. Instead of waiting days for tissue samples to process, the new method cuts the time down to hours while maintaining the same quality of detailed images. The technique was successfully tested on tadpole and fruit fly brains, showing it could be useful for studying neural structures and potentially applied to studying brain diseases like Alzheimer’s.

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