tight junction proteins

From Structure to Function: How Prebiotic Diversity Shapes Gut Integrity and Immune Balance

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This comprehensive review explains how prebiotics—special dietary fibers that feed beneficial gut bacteria—help maintain a healthy digestive system and strong immune response. By nourishing good bacteria and directly strengthening the intestinal barrier, prebiotics can reduce harmful inflammation and potentially lower cancer risk. Different types of prebiotics like inulin and resistant starch work through both bacterial fermentation and direct immune cell interaction, making them promising tools for preventing various diseases.

Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

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A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

The Effect of 2′-Fucosyllactose on Gut Health in Aged Mice

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This research shows that 2′-fucosyllactose, a natural compound found in breast milk, can significantly improve gut health in older mice. The treatment strengthened the intestinal barrier, reduced harmful inflammation, and increased beneficial bacteria populations. These findings suggest that 2′-FL could be developed as a food supplement to help older people maintain better digestive and immune health.

Winning the battle of intestinal peace with Bacillus—a multifaceted approach to animal health, immunity, and future applications in monogastric livestock production

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This review examines how Bacillus bacteria, when added to animal feed, can improve the health and growth of chickens and pigs. These bacteria work by producing beneficial compounds that strengthen the gut, improve digestion, reduce harmful bacteria, and boost the immune system. Bacillus probiotics offer a natural alternative to antibiotics, helping reduce antibiotic resistance while keeping animals healthier and more productive.

A novel synbiotic formulation prevents calcium oxalate stones by restoring gut microbiota homeostasis

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This study tested a special probiotic and prebiotic combination to prevent kidney stones caused by too much oxalate in the body. The formula containing three beneficial bacteria strains and a plant-based fiber worked better than any single component alone. The treatment restored healthy gut bacteria, protected the intestinal lining, and reduced the amount of oxalate reaching the kidneys, effectively preventing stone formation in animal models.

Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

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This study found that two types of plant fungi, Podosphaera fusca and Peronospora ficariae, can trigger asthma-like reactions in mice similar to known allergens. While these fungi produce weaker responses than the standard allergen ovalbumin, they still cause significant inflammation, immune activation, and airway changes. The research suggests these plant parasites should be added to the list of recognized allergens that may trigger respiratory problems in humans.

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

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Natural plant and organism sugars called polysaccharides can improve your gut health by feeding beneficial bacteria and strengthening your intestinal barrier. These compounds help prevent diseases like obesity, diabetes, and inflammatory bowel disease by changing the types of bacteria in your gut and producing helpful substances. Polysaccharides come from common foods like mushrooms, seaweed, berries, and vegetables, making them potential natural treatments for various health conditions.

Potential relationship between gut microbiota and animal diarrhea: a systematic review

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This review explains how the trillions of microorganisms living in animal intestines are crucial for health and digestion. When these microbial communities become imbalanced, animals develop diarrhea, which is a major problem in farming causing economic losses and animal suffering. The review shows that adding beneficial bacteria (probiotics) and their food sources (prebiotics) to animal diets can restore balance and prevent diarrhea, offering practical solutions to reduce the need for antibiotics.

Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application

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This review explores how probiotics (beneficial live bacteria) can help treat inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. Probiotics work by restoring healthy bacteria balance in the gut, strengthening the intestinal barrier, and calming the immune system’s inflammatory response. While more research is needed, particularly for Crohn’s disease, probiotics show promise as a safe, long-term treatment option that can complement standard medications and improve patients’ quality of life.

Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broilers

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Researchers studied how a medicinal mushroom extract called Phellinus linteus polysaccharides could help broiler chickens recover from immune stress caused by bacterial toxins. The supplement improved the chickens’ growth, reduced harmful inflammatory responses, and promoted beneficial gut bacteria while reducing harmful ones. The treatment strengthened the intestinal barrier and restored the chickens’ natural antioxidant defenses. This suggests the mushroom supplement could be a natural alternative to antibiotics for improving poultry health on farms.

Research Keyword: tight junction proteins