Research Keyword: Thailand

Clinical and Genomic Insights into Antifungal Resistance in Aspergillus Isolates from Thailand

Researchers in Thailand found that certain fungal infections caused by Aspergillus fumigatus are becoming resistant to common antifungal medications like voriconazole. They identified a specific genetic mutation called TR34/L98H in one patient sample that makes the fungus resistant to azole drugs used to treat these serious infections. By analyzing the genetic makeup of these resistant fungi, scientists discovered additional changes beyond the known resistance gene, suggesting these organisms may adapt in multiple ways to survive treatment. This is the first time this particular resistance mutation has been detected in a clinical patient sample in Thailand, indicating that antifungal resistance in Aspergillus is spreading and requires closer monitoring and testing.

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Phylogenetic diversity of Colletotrichum species (Sordariomycetes, Glomerellales, Glomerellaceae) associated with plant diseases in Thailand

Researchers in Thailand studied a common fungal plant pathogen called Colletotrichum that causes diseases like anthracnose and leaf spots on various plants. They identified eight different species of this fungus and discovered two previously unknown species. The study helps farmers and plant scientists better understand and identify these disease-causing fungi to protect their crops.

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