Research Keyword: terpenoids

Fungal Bioactive Compounds as Emerging Therapeutic Options for Age-Related Neurodegenerative Disorders

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Mushrooms contain special compounds that may help protect our brains as we age. These fungal compounds fight inflammation, reduce harmful free radicals, and help clear out damaged cellular parts—all things that slow down brain aging and diseases like Alzheimer’s and Parkinson’s. While the research looks very promising in lab and animal studies, scientists still need to figure out how to make these compounds work better in the human body and prove they’re safe and effective in patients.

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Biologically active secondary metabolites from white-rot fungi

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White-rot fungi are special mushrooms that can break down wood and produce unique chemical compounds with amazing health benefits. These compounds have been found to fight cancer, kill harmful bacteria, reduce inflammation, and protect nerve cells. Scientists are excited about using these natural fungal compounds to create new medicines and treat various diseases in the future.

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Whole-Genome Sequencing and Comparative Genomics Analysis of the Wild Edible Mushroom (Gomphus purpuraceus) Provide Insights into Its Potential Food Application and Artificial Domestication

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Scientists sequenced the complete genetic code of Gomphus purpuraceus, a wild mushroom eaten in southwest China for hundreds of years. By comparing its genes to other edible mushrooms, researchers discovered it likely forms beneficial partnerships with trees and can break down some plant material. The study shows this mushroom can efficiently use simple sugars like sucrose and maltose for growth, which could help farmers grow it commercially while preserving this rare species.

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New bioactive secondary metabolites from fungi: 2024

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Scientists discovered 907 new compounds from fungi in 2024, with most being terpenoids and polyketides that show promise as medicines. These fungal compounds demonstrate strong activity against bacteria, fungi, and inflammation, with some showing potential against cancer and diabetes. The research uses advanced techniques like genome mining and metabolomics to find these compounds more efficiently. This accelerating discovery rate suggests fungi could be a major source for developing new drugs to treat various diseases.

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Evidence-Based Nutraceuticals Derived from Antrodia cinnamomea

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Antrodia cinnamomea, a mushroom from Taiwan traditionally used for health, contains many beneficial compounds that fight inflammation, tumors, and oxidative stress. Research shows it can help with cancer, liver disease, diabetes, and high blood pressure. The mushroom can be grown in laboratories and its active compounds extracted using various modern techniques, making it promising for health supplements and medicines.

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