Research Keyword: synbiotics

In-ovo injection of Bacillus subtilis, raffinose, and their combinations enhances hatchability, gut health, nutrient transport- and intestinal function-related genes, and early development of broiler chicks

Researchers injected newly developing chicken eggs with beneficial bacteria (Bacillus subtilis) and a prebiotic substance (raffinose) to improve chick health. The treatment enhanced egg hatchability, improved chick weight, reduced harmful bacteria in the gut, and strengthened intestinal function. This approach shows promise as a natural alternative to antibiotics in poultry farming.

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Nutritional strategies in supporting immune checkpoint inhibitor, PI3K inhibitor, and tyrosine kinase inhibitor cancer therapies

This review examines how nutrition and food-based interventions can improve cancer treatment outcomes for patients receiving targeted cancer therapies. A Mediterranean-style diet with plenty of fiber (30-50g daily) appears beneficial for patients on immune checkpoint inhibitor therapies by promoting healthy gut bacteria that support immune function. The review also discusses promising research on fermented foods, specific bacterial supplements, mushroom extracts, and fasting approaches as complementary strategies to enhance cancer treatment effectiveness while reducing side effects.

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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)

Researchers studied a kombucha tea drink enriched with fiber from chicory root in healthy adults over six weeks. The study found that people who consumed the fiber-enriched kombucha had lower triglyceride levels (blood fats) and beneficial changes in their gut bacteria, particularly an increase in Bifidobacterium, a bacteria known to support digestive health. These results suggest that this type of kombucha could be beneficial for metabolic and gut health, though more research is needed to confirm these benefits.

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Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne

This study tested two supplements for treating non-cystic acne: one containing probiotics and herbs, and another based on myoinositol and medicinal plants. Both supplements significantly reduced acne lesions and improved gut health by increasing beneficial bacteria and beneficial fatty acids produced by these bacteria. The myoinositol-based supplement also reduced hormone precursors related to acne development. These findings suggest that supporting gut health may be an effective way to treat acne.

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Efficacy of prebiotic, probiotic and synbiotic administration in improving growth in children aged 0–59 months living in low- and middle-income countries: a systematic review and meta-analysis

This comprehensive review examined whether giving children special dietary supplements containing beneficial bacteria and their food sources (prebiotics, probiotics, or synbiotics) helps them grow better in low-income countries. The analysis of eight studies found that these supplements may help children gain weight, especially those who are malnourished, though the evidence remains limited. More research is needed to fully understand whether these supplements are truly effective for promoting healthy growth in young children.

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A comprehensive overview of the effects of probiotics, prebiotics and synbiotics on the gut-brain axis

This comprehensive review examines how probiotics (beneficial live bacteria), prebiotics (food for beneficial bacteria), and synbiotics (combinations of both) can influence communication between the gut and brain. These interventions can produce beneficial compounds like GABA and serotonin, strengthen the gut barrier, and reduce inflammation, potentially helping with mood, anxiety, cognition, and various digestive disorders. However, effects vary greatly depending on the specific strain used, dosage, and individual differences in gut bacteria, and more large-scale studies are needed to confirm long-term clinical benefits.

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Investigating the Knowledge of Prebiotics, Probiotics, and Synbiotics That May Help to Improve the Gut-Organ Axis Function in Middle-Aged and Older Adults

This study examined what middle-aged and older adults know about probiotics, prebiotics, and synbiotics—special food components that can improve gut health. Researchers found that many people had little knowledge about these products, even though they may help with various health conditions including heart disease and mental health. After giving people an educational information sheet about gut biotics, their knowledge significantly improved, suggesting that simple education can help people make better choices about their digestive health.

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Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery

Scientists created a new type of yogurt that contains beneficial bacteria and special prebiotics from rice straw. The innovation uses tiny nanoparticles to protect some of the prebiotics so they reach your gut intact, while free prebiotics immediately feed the beneficial bacteria in the yogurt during storage. This dual-delivery approach keeps the yogurt fresher longer while ensuring you get maximum health benefits for your digestive system.

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In vitro compatibility screening of Bacillus pumilus and Bacillus altitudinis strains with selected candidate prebiotics for in ovo application of synergistic synbiotics

Researchers tested different beneficial bacteria (Bacillus strains) and food additives (prebiotics) to create improved formulations for chicken embryos. They found that certain plant-based additives, especially protein hydrolysate, worked particularly well with specific bacterial strains. When they tested the best combination in developing chicken eggs, it was completely safe and didn’t affect hatching rates, suggesting this approach could be used to give chicks a healthier start in life.

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