surgical debridement

Epidemiology and outcomes of Candida-associated osteoarticular infections: A multicentre retrospective study from Turkey

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This study examined 73 patients in Turkey who developed bone and joint infections caused by Candida fungi over ten years. The researchers found that diabetes was very common among patients and made recovery harder, while surgery to clean out infected tissue significantly improved outcomes. Importantly, they discovered resistance to common antifungal medications was higher in certain Candida species compared to others.

Continuous debridement combined with short-term posaconazole therapy for cutaneous mucormycosis caused by Rhizopus oryzae infection secondary to acute myeloid leukemia: a case report

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An 80-year-old patient with acute myeloid leukemia developed a serious fungal skin infection caused by Rhizopus oryzae on his lower leg. Doctors treated the infection by repeatedly cleaning out the infected tissue and giving him an antifungal medication called posaconazole for just one week. Despite the short treatment duration due to cost concerns, the patient’s wound gradually healed over four months through continued surgical care, showing that sometimes focused surgical treatment can be as effective as long-term medication.

Successful Treatment of Fungal Dermatitis in a Bottlenose Dolphin (Tursiops truncatus)

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A bottlenose dolphin at a Japanese aquarium developed a serious fungal infection on its tail fin while suffering from severe digestive problems and weight loss. The infection was caused by two types of fungi that are normally hard to treat because they resist many antifungal medications. Veterinarians successfully treated the dolphin using a combination of two antifungal drugs (voriconazole and terbinafine), surgical removal of dead tissue, and daily wound cleaning with special solutions. The dolphin’s wound eventually healed completely, and this is the first documented successful treatment of these particular fungal infections in bottlenose dolphins.

Cutaneous Mucormycosis Following Polytrauma: A Multidisciplinary Approach

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A 22-year-old man suffered severe injuries from a motorcycle-truck collision that damaged his perineal area and left thigh. Despite antibiotics and wound therapy, a dangerous fungal infection called mucormycosis developed in the wound. The medical team treated this by repeatedly removing infected tissue, using powerful antifungal medications (amphotericin B and posaconazole), and carefully managing the wound with special therapy before skin grafting, ultimately achieving successful healing.

Rhino sinusitis caused by Lasiodiplodia theobromae in a diabetic patient

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A 56-year-old diabetic man developed a sinus infection caused by a rare fungus called Lasiodiplodia theobromae, which typically affects plants. The infection was diagnosed through laboratory testing and DNA sequencing, as traditional identification methods were inconclusive. The patient was successfully treated with a combination of sinus surgery and a six-week course of antifungal medication, showing complete recovery after one year of follow-up.

A Rare Battle: Multidisciplinary Care for a Child with Rhino-Orbital Cerebral Mucormycosis in Somali Region of Ethiopia

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A 12-year-old girl with poorly controlled diabetes developed a serious fungal infection in her sinuses and eye that spread to her brain. Despite the infection being extremely dangerous, doctors successfully treated her using multiple approaches including antifungal medication, surgery to remove infected tissue, and careful management of her blood sugar. She recovered and went home, though she lost vision in one eye.

A case report of Saksenaea vasiformis mucormycosis infection of a lower segment caesarean section wound

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A young woman developed a rare fungal infection (mucormycosis) in her caesarean section wound seven days after surgery. Despite initial antibiotic treatment, she required multiple surgical debridement procedures combined with antifungal medications to eliminate the infection. The surgical team successfully reconstructed her abdominal wall using specialized mesh and skin grafting techniques, resulting in complete healing.

Successful management of Lomentospora prolificans septic arthritis and osteomyelitis in an immunocompetent child: A case report

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A 3-year-old boy developed a serious fungal bone and joint infection caused by Lomentospora prolificans after surgery to fix a broken elbow. This fungus is extremely resistant to most antifungal medications. The infection was successfully treated using multiple approaches: aggressive surgical cleaning, several different antifungal drugs used together, special antibiotic-loaded bone cement, and antiseptic rinses. After two months of intensive treatment, the infection cleared and the child’s arm was saved from amputation.

Invasive nasal and paranasal mucormycosis in a patient with severe dengue fever and multiple risk factors: A case report and literature review

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A 50-year-old woman in Vietnam developed a rare and deadly fungal infection called mucormycosis while recovering from dengue fever. She had weakened immunity from taking steroids for other conditions and from the dengue virus itself. The infection caused black, dead tissue to rapidly spread in her nose and around her eye. Despite treatment with antifungal medications, the infection progressed, and she died within days. The case shows how important it is to watch for dangerous opportunistic infections in dengue patients, especially those already dealing with weakened immune systems.

Saksenaea oblongispora Rhinosinusitis in Advanced HIV: A Rare and Lethal Mucormycosis

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A 32-year-old man with advanced HIV developed a severe fungal infection of his sinuses caused by a rare fungus called Saksenaea oblongispora, which typically doesn’t affect people with HIV. The patient presented with severe facial swelling that rapidly worsened, and despite doctors identifying the fungus through biopsies and lab tests, he did not receive antifungal treatment or surgery before his condition became critical. This is the first case of this particular fungal infection documented in sub-Saharan Africa and in HIV patients, highlighting how dangerous this rare infection can be and how challenging it is to diagnose quickly enough to save lives.

Research Keyword: surgical debridement