Research Keyword: succinate dehydrogenase

An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists developed new chemical compounds called indole derivatives that can kill harmful fungi that destroy fruit crops like stone fruits and grapes. These compounds were made using microwave heating, which is faster and more efficient than traditional methods. Testing showed that some of these new compounds were even better at fighting these fungal diseases than current commercial fungicides, offering promise for protecting crops in agriculture.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists created new chemical compounds based on indole structures that can kill harmful fungi that destroy fruit crops. These compounds were made more efficiently using microwave heating and tested against two major crop pathogens that cause billions of dollars in losses annually. The most promising compound (A) proved even more effective than commercial fungicides at stopping fungal growth and spore germination. This research could lead to better, safer alternatives for protecting crops from fungal diseases.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists created new chemical compounds based on indole molecules that can effectively kill two harmful fungi that destroy fruit crops. These compounds were made using microwave heating, which is faster and more efficient than traditional methods. Tests showed that some of these new compounds work even better than commercial fungicides at killing these fungi, and they may work by blocking an important energy-producing process in the fungal cells.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Researchers created new chemical compounds based on indoles that can kill harmful fungi affecting fruit crops. These compounds were made using microwave energy, which made the synthesis faster and more efficient. Testing showed that some of these new compounds worked better at stopping fungal growth and spore germination than currently used commercial fungicides, making them promising candidates for protecting fruit crops from rot diseases.

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One-Pot Synthesis of Chiral Succinate Dehydrogenase Inhibitors and Antifungal Activity Studies

Scientists developed a new method to create potent antifungal medications that can protect crops from destructive fungal diseases. By carefully controlling the molecular structure (chirality) of the compounds, they created drugs that are significantly more effective and potentially less toxic than existing treatments. Testing showed that the new compound called (S)-5f works 76 times better against gray mold fungus than its mirror-image counterpart, similar to how your left and right hands have the same shape but can’t be superimposed.

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