Research Keyword: substrate specificity

Functional analysis of a novel endo-β-1,6-glucanase MoGlu16 and its application in detecting cell wall β-1,6-glucan of Magnaporthe oryzae

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Scientists discovered and studied a special enzyme called MoGlu16 from rice blast fungus that breaks down a key component of fungal cell walls called β-1,6-glucan. This enzyme can be used to visualize where this cell wall component is located in the fungus at different stages of its life cycle. When applied to fungus spores, the enzyme prevents them from sprouting and forming infection structures, making it a promising candidate for developing new ways to control rice blast disease.

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Kinetics of Manganese Peroxidase Using Simple Phenolic Compounds as Substrates

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Researchers studied how manganese peroxidase, an enzyme produced by soil fungi, breaks down simple phenolic compounds found in plants. They tested three compounds with different structures and found that those without carboxylic acid groups (like pyrogallol) are better substrates for the enzyme and produce more stable products that accumulate in soil. This research helps explain how plant compounds contribute to soil health and nutrient cycling.

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L-Rhamnose Dehydrogenase LraA of Aspergillus niger Shows High Substrate Specificity Matching Its Expression Profile

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Scientists studied an enzyme called LraA found in a common fungus (Aspergillus niger) that breaks down L-rhamnose, a sugar found in plant cell walls. They discovered that this enzyme is extremely selective and only works on L-rhamnose, unlike most other similar enzymes that can process multiple types of sugars. This makes it very useful for biotechnology applications where researchers want to specifically convert L-rhamnose without affecting other pathways.

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Identification of a fungal antibacterial endopeptidase that cleaves peptidoglycan

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Scientists discovered a new antibacterial protein called CwhA produced by the fungus Aspergillus fumigatus that acts like molecular scissors, cutting apart the cell walls of harmful bacteria like Staphylococcus aureus. This protein is produced by the fungus when it encounters bacteria in the lungs during infection and helps the fungus fight off bacterial competitors. When CwhA cuts up bacterial cell walls, it creates fragments that alert the immune system, potentially boosting the body’s defense response against infection.

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