Research Keyword: submerged cultivation

Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

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This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

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Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity

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Researchers isolated a new oyster mushroom strain and studied how it affects digestive system health. They compared the fruiting body and mycelium (root-like structure) and found that water extracts of the fruiting body were rich in beneficial compounds like β-glucans and antioxidants. When tested on stomach muscle tissue, these extracts caused muscle contractions in a dose-dependent manner, suggesting potential benefits for digestive function. This discovery could lead to new natural supplements supporting gut health.

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Airlift bioreactor–based strategies for prolonged semi-continuous cultivation of edible Agaricomycetes

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Scientists studied how to grow medicinal mushrooms in liquid bioreactors to produce health-beneficial compounds called glucans more efficiently. By testing different feeding rates in specially designed fermentation systems, they found that Trametes versicolor (turkey tail mushroom) grows best at a moderate feeding rate, producing substantial amounts of glucans—compounds known to support immune function and reduce blood sugar levels. This research shows that growing medicinal mushrooms in controlled bioreactors could be much more efficient and faster than traditional farming methods.

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Functionalized Micellar Membranes from Medicinal Mushrooms as Promising Self-Growing Bioscaffolds

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Researchers created special membranes from medicinal mushrooms that could be used for wound healing and skin repairs. These membranes were grown in laboratory conditions and then treated with mango peel extract, which gave them antimicrobial properties to fight bacteria. The membranes are biodegradable, environmentally friendly, and work similar to the structure of skin tissue, making them promising for medical applications.

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Functionalized Micellar Membranes from Medicinal Mushrooms as Promising Self-Growing Bioscaffolds

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Scientists created special membranes from medicinal mushrooms that can help heal wounds and regenerate damaged skin. These membranes are grown naturally in liquid culture and enriched with extract from mango peels to fight bacteria and promote healing. The material is completely natural, biodegradable, and performs better than many conventional wound healing materials, making it an eco-friendly option for medical applications.

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Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers

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Researchers tested whether mushroom mycelium grown using agricultural waste could be safely added to chicken feed. The mycelium, rich in beneficial compounds like β-glucans, was added to broiler diets at varying levels for 35 days. Results showed that chickens fed diets containing up to 5% mushroom mycelium performed just as well as control chickens, with no negative effects on health, digestion, or metabolism, suggesting this sustainable feed ingredient could help reduce competition between animal feed and human food.

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Screening of Basidiomycete Strains Capable of Synthesizing Antibacterial and Antifungal Metabolites

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Researchers tested 18 different types of wood-decay fungi (basidiomycetes) to see if they could produce natural antibiotics and antifungal compounds. They found that 16 of the 18 strains successfully produced antimicrobial substances. Five strains were particularly promising, showing strong activity against dangerous bacteria including antibiotic-resistant strains. The study identified specific chemical compounds from these fungi that could potentially be developed into new medicines.

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