Research Keyword: subcutaneous mycosis

Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

Fungal infections are serious health threats that kill approximately 1.5 million people annually worldwide. This comprehensive review identifies over 280 different fungal species that can infect humans, with Aspergillus being the most dangerous genus. The study provides updated information on how these infections are diagnosed through various methods including cultures, microscopy, and molecular testing, as well as treatment options ranging from traditional antifungal drugs to newer therapies like nanotechnology-based formulations.

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Surgical management of deep dermatophytosis in a patient with CARD9 deficiency

A 23-year-old man from North Africa with a genetic immune disorder (CARD9 deficiency) developed a serious fungal skin infection with deep tissue involvement. The infection caused multiple pus-filled pockets and hair loss on his scalp. Doctors treated him with both antifungal medications and surgery to drain the infected areas, resulting in complete healing after two weeks.

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Sporothrix davidellisii: A new pathogenic species belonging to the Sporothrix pallida complex

Scientists have identified a new fungal species called Sporothrix davidellisii that causes an infection in cats. This fungus was found in an infected cat in Australia and is related to other fungi that cause sporotrichosis, a skin disease in humans and animals. The discovery shows that cats can help scientists identify new fungal pathogens in their environments, making them important sentinels for tracking emerging diseases.

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Extensive and recurrent infection caused by Medicopsis romeroi in two immunocompromised patients

This case report describes two patients with weakened immune systems who developed serious fungal skin infections caused by a rare mold called Medicopsis romeroi. Both patients underwent multiple surgeries and required extended antifungal medication treatment lasting months to years. The study demonstrates that successful treatment requires a combination approach including surgical removal of infected tissue, adjustment of immunosuppressive medications, and prolonged antifungal therapy.

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