Research Keyword: SUB6 gene deletion

SUB6 Subtilisin is Involved During the Initial Adhesion of Trichophyton benhamiae and T. mentagrophytes onto Reconstructed Human Epidermis

This study examined how a fungal protein called SUB6 helps dermatophytes (fungi causing ringworm) stick to human skin. Researchers used genetically modified fungi without SUB6 and found that these strains had difficulty initially attaching to skin but eventually infected it anyway. The results suggest SUB6 is a useful marker for detecting fungal infections but isn’t absolutely necessary for the fungus to cause disease.

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