Research Keyword: stress response

A Possible Involvement of Sialidase in the Cell Response of the Antarctic Fungus Penicillium griseofulvum P29 to Oxidative Stress

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Researchers studied a special fungus from Antarctica that produces an enzyme called sialidase. When temperatures dropped dramatically, the fungus activated this enzyme along with other protective defenses to survive. The study found that under extreme cold stress, sialidase activity increased significantly, suggesting it helps the fungus protect itself from oxidative damage caused by freezing temperatures. This is the first discovery showing sialidase plays an important role in how Antarctic fungi survive in their extreme environment.

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Low temperature, mechanical wound, and exogenous salicylic acid (SA) can stimulate the SA signaling molecule as well as its downstream pathway and the formation of fruiting bodies in Flammulina filiformis

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Researchers studied how cooling, physical damage, and a plant hormone called salicylic acid can trigger fruiting body formation in an edible mushroom called Flammulina filiformis. They discovered that these treatments activate specific genes in the mushroom that control fruit production. This research helps explain why mushroom farmers use these methods and could improve mushroom cultivation efficiency.

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The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans

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Researchers studied three important protein switches (Rab GTPases) in a fungus that causes cabbage wilt disease. By deleting these proteins one at a time, they found that each plays a critical role in fungal growth, spore production, and the ability to infect plants. The findings suggest that targeting these proteins could be a strategy to control the devastating cabbage wilt disease.

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Integrated Transcriptomic and Proteomic Analyses Reveal Molecular Mechanism of Response to Heat Shock in Morchella sextelata

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Morels are delicious mushrooms that are difficult to grow because they are very sensitive to high temperatures. Scientists compared two different morel strains to understand why one variety can tolerate heat better than the other. By studying the genes and proteins expressed at normal and high temperatures, researchers discovered that the heat-tolerant strain activates specific protective mechanisms, particularly through a protein called Rsp5 that helps boost other protective proteins. This research provides valuable information for breeding morel varieties that can survive warmer growing conditions in the age of climate change.

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The protein kinases family in fungi: adaptability, virulence and conservation between species

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Protein kinases are cellular ‘switches’ that help fungi survive harsh conditions by regulating how cells make proteins and adapt to stress. A particularly important kinase called GCN2 acts as a sensor that detects when fungi lack amino acids, triggering a survival response that helps the fungus adapt and maintain pathogenicity. This review shows how understanding GCN2 could help scientists develop new antifungal drugs to treat fungal infections.

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Whole Genome Sequence of an Edible Mushroom Stropharia rugosoannulata (Daqiugaigu)

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Scientists have decoded the complete genetic blueprint of the wine cap mushroom (Stropharia rugosoannulata), a popular edible mushroom grown worldwide. The research identified over 12,000 genes and discovered the mushroom contains powerful enzymes that break down plant material, explaining why it grows so well on straw and corn stalks. The study also revealed that different parts of the mushroom (cap and stem) have different functions, with stems focusing on energy production and caps on growth and development.

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The regulatory variant rs1950834 confers the risk of depressive disorder by reducing LRFN5 expression

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Researchers identified a genetic variant (rs1950834) that increases depression risk by reducing production of LRFN5, a protein important for brain connections. They found this variant affects how brain cells in a region called the nucleus accumbens produce LRFN5. When LRFN5 levels are low, mice become more depressed and sensitive to stress, but boosting LRFN5 protects against depression. This discovery could lead to new ways to diagnose and treat depression.

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