Novochizol, a new type of chitosan-based treatment, helps wheat plants defend themselves against stem rust by triggering natural immune responses. When wheat seedlings are treated with Novochizol four days before rust infection, the plants accumulate protective molecules like hydrogen peroxide and phenolic compounds that kill many of the rust fungus colonies before they can spread. This reduces disease damage by 50-55% compared to untreated plants, offering a promising biological alternative to synthetic fungicides.