SSRI – mycolab.ai

Comparing Antidepressant Effects of Psilocybin-Assisted Psychotherapy in Individuals That Were Unmedicated at Initial Screening Versus Individuals Discontinuing Medications for Study Participation

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This study compared how well psilocybin therapy works for people with treatment-resistant depression depending on whether they were already off antidepressants or had stopped taking them for the study. The researchers found that both groups improved similarly in depression and anxiety symptoms after receiving psilocybin with therapy support. These results suggest that stopping antidepressants before psilocybin treatment may not reduce its effectiveness, though more research is needed to fully understand the relationship between medication status and treatment outcomes.

Negative affective bias in depression following treatment with psilocybin or escitalopram – a secondary analysis from a randomized trial

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This research compared how psilocybin mushrooms and escitalopram (a common antidepressant) affect the way depressed people perceive emotions. Both treatments helped patients become better at recognizing positive facial expressions and less likely to misinterpret neutral or positive faces as negative. Interestingly, while both treatments improved emotional processing similarly, the improvements were connected to later mood improvement in different ways for each drug, suggesting they may work through somewhat different mechanisms in the brain.

Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicine

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This review examines how psychedelic drugs like ketamine, MDMA, and psilocybin could offer new hope for people with PTSD by working on the brain differently than current medications. These compounds work quickly and help the brain form new neural connections that can help people process traumatic memories more effectively. When combined with therapy, these drugs show promise in reducing PTSD symptoms faster and more effectively than traditional antidepressants. The review also explains how doctors could use personalized medicine approaches using brain scans and genetic testing to determine which treatment would work best for each individual patient.

Research Keyword: SSRI

Comparing Antidepressant Effects of Psilocybin-Assisted Psychotherapy in Individuals That Were Unmedicated at Initial Screening Versus Individuals Discontinuing Medications for Study Participation

Negative affective bias in depression following treatment with psilocybin or escitalopram – a secondary analysis from a randomized trial

Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicine