Research Keyword: skin biopsy

Photo Quiz: Asteroid bodies in a skin biopsy of a farmer

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A farmer developed nodular skin lesions two weeks after a wrist injury during farming activities, which turned out to be sporotrichosis, a fungal infection caused by Sporothrix globosa. Skin biopsy revealed characteristic structures called asteroid bodies that helped suggest the diagnosis. The infection was confirmed through fungal culture and DNA testing, and was successfully treated with potassium iodide over six months.

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Photo Quiz: Asteroid bodies in a skin biopsy of a farmer

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A farmer developed a chain of red nodules on his arm after a wrist injury, which was diagnosed as sporotrichosis, a fungal infection caused by Sporothrix globosa. The diagnosis was confirmed through tissue biopsy, which showed distinctive asteroid bodies – yeast cells surrounded by radiating material that represents the body’s immune response. The infection was successfully treated with oral potassium iodide over 6 months, resulting in complete healing.

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Editorial: Dermatopathology and Associated Laboratory Investigations in the Study of Skin Disease

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This special journal issue brings together several studies on how doctors diagnose skin diseases using laboratory tests. The papers cover different methods including examining fungal infections under a microscope, using new staining techniques, and applying molecular tests to identify skin cancers and autoimmune conditions. Together, these studies show how combining pathology examination with laboratory techniques is essential for accurately diagnosing and treating various skin disorders.

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Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report

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A 69-year-old woman with breast cancer developed a skin infection caused by a rare fungus called Cladophialophora boppii while taking dexamethasone for cancer treatment. Doctors diagnosed the infection through skin biopsy and fungal testing, then removed the infected area surgically. After three weeks of antifungal medication (itraconazole), the infection cleared completely and did not return during four months of follow-up. This case suggests that surgery combined with short-term antifungal treatment may be sufficient for this type of infection.

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