Research Keyword: skin barrier

Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur

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Malassezia furfur is a common skin fungus that can change from round yeast cells to thread-like filaments. When it becomes thread-like, it produces a special enzyme called MfSAP2 that damages the proteins holding together the dead skin cells that form our skin’s protective barrier. This damage may be responsible for the patches and discoloration seen in pityriasis versicolor, a common skin condition.

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Development of dihydrooxyresveratrol-loaded nanostructured lipid carriers for safe and effective treatment of hyperpigmentation

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This research developed a new skin-brightening treatment using nanoparticles to deliver oxyresveratrol and its modified form (DHO) more effectively to the skin. The scientists improved the stability of these compounds by creating tiny lipid-based carriers that protect them from light damage and help them penetrate the skin barrier. Testing showed these formulations safely reduced melanin production without harming healthy skin cells, offering promise for cosmetic products to treat dark spots and hyperpigmentation.

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Safe and Effective Antioxidant: The Biological Mechanism and Potential Pathways of Ergothioneine in the Skin

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Ergothioneine is a natural compound found in certain fungi and bacteria that acts like a powerful antioxidant in the body. When applied to skin, it can protect against damage from sun exposure and environmental pollution, reduce signs of aging, and help calm inflammation. It’s particularly special because it automatically travels to damaged areas in the skin where it’s needed most, making it an efficient and targeted treatment ingredient for cosmetics.

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