Research Keyword: short-chain fatty acids

Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial

This study tested whether adding powdered oyster mushrooms to a meal could help people with impaired glucose tolerance manage their blood sugar and appetite. While the mushroom powder didn’t reduce blood glucose spikes as expected, it did lower fat levels in the blood, increase a hormone that promotes fullness, and reduced hunger. The results suggest that adding oyster mushroom powder to meals could be a simple dietary change that helps prevent diabetes and weight gain.

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Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

Natural plant and organism sugars called polysaccharides can improve your gut health by feeding beneficial bacteria and strengthening your intestinal barrier. These compounds help prevent diseases like obesity, diabetes, and inflammatory bowel disease by changing the types of bacteria in your gut and producing helpful substances. Polysaccharides come from common foods like mushrooms, seaweed, berries, and vegetables, making them potential natural treatments for various health conditions.

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Effects of Chronic Barley Consumption on Upper Respiratory Tract Symptoms in Japanese Healthy Adults: A Randomized, Parallel-Group, Controlled Trial

This study found that eating cooked waxy barley daily for 8 weeks reduced sneezing and nasal congestion in healthy adults compared to those eating white rice. Participants who ate barley also reported feeling less tired and experienced improved mood. The barley contains a fiber called β-glucan that appears to boost the body’s natural immune cells, helping protect against cold symptoms.

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Effects of Short-Chain Fatty Acid Combinations Relevant to the Healthy and Dysbiotic Gut upon Candida albicans

Short-chain fatty acids produced by healthy gut bacteria appear to slow the growth and reduce the invasive characteristics of Candida albicans, a fungus that normally lives harmlessly in the gut but can cause infections when the microbiota is disrupted by antibiotics. This study tested whether healthy gut SCFA levels inhibit Candida more effectively than dysbiotic levels and found that the healthy SCFA mix was somewhat more effective at preventing fungal hyphal formation, which is important for tissue invasion. However, different Candida strains responded differently to the SCFAs, suggesting that individual variation affects how protective these bacterial metabolites can be.

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Human Gut Microbiome: A Connecting Organ Between Nutrition, Metabolism, and Health

Your gut bacteria function like an extra organ, helping digest food and producing important compounds that affect your whole body. The type of bacteria in your gut depends on diet, delivery method at birth, and antibiotics you’ve taken. Eating more fiber and taking certain probiotics can improve your bacterial balance and help prevent diseases like diabetes, obesity, and heart problems. This suggests that managing your gut microbiome through diet might be just as important as taking traditional medicines for staying healthy.

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The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy

Sepsis can cause brain dysfunction called sepsis-associated encephalopathy, leading to memory problems and confusion in about one-third to two-thirds of sepsis patients. The bacteria in your gut communicate with your brain through multiple pathways, and when sepsis disrupts this communication, it causes harmful inflammation in the brain. Treatments like probiotics and transplanting healthy gut bacteria from donors show promise in animal studies and early human trials for improving memory and cognitive function after sepsis.

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Influence of Pleurotus sapidus fruiting bodies on the performance, cecal microbiome, and gene expression in the liver and breast muscle of broilers

Researchers tested whether edible mushroom fruiting bodies could be used as animal feed for chickens. They found that chickens fed diets containing oyster mushroom (Pleurotus sapidus) had reduced growth and lower nutrient absorption compared to control chickens. While mushroom-based feed appeared to increase beneficial gut bacteria diversity, it ultimately impaired overall chicken performance, suggesting mushroom fruiting bodies are not suitable as a primary feed component for commercial poultry production.

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Three Different Types of β-Glucans Enhance Cognition: The Role of the Gut-Brain Axis

Researchers tested three types of β-glucans—fiber compounds found in mushrooms, oats, and other foods—to see if they could improve memory in mice. All three types enhanced recognition memory and reduced brain inflammation, while only oat β-glucan significantly changed gut bacteria composition. The findings suggest that different β-glucans may help prevent cognitive decline through different mechanisms involving the gut-brain connection.

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