Research Keyword: sesquiterpene

Sandalwood Sesquiterpene (Z)-α-Santalol Exhibits In Vivo Efficacy Against Madurella mycetomatis in Galleria mellonella Larvae

Researchers tested sandalwood compounds against a fungal infection that causes a tropical disease called eumycetoma. Using a laboratory model with wax moth larvae infected with the fungus, they found that a specific compound called (Z)-α-santalol significantly extended the survival of infected larvae. This compound was more effective than current antifungal drugs and showed promise as a potential new treatment for this neglected tropical disease.

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Isolation, (bio)synthetic studies and evaluation of antimicrobial properties of drimenol-type sesquiterpenes of Termitomyces fungi

Termite colonies farm a fungus called Termitomyces for food in an ancient partnership. Scientists discovered that the mushrooms produced by this fungus release distinctive chemical signals, particularly a compound called drimenol. By isolating and synthesizing these compounds, researchers found they have antimicrobial properties and may play a role in communicating between termites and their fungal crop or protecting mushrooms from infection.

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