Research Keyword: serology

Diagnostic performance of Aspergillus-specific immunoglobulin G immunochromatographic and enzyme-linked immunosorbent assay testing in chronic pulmonary aspergillosis: comparative analysis across subtypes and influencing factors

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This study compared two blood tests for diagnosing chronic pulmonary aspergillosis (CPA), a chronic fungal lung infection caused by Aspergillus. The rapid immunochromatographic test (ICT) performed better overall than the traditional ELISA laboratory test, making it more useful as a quick diagnostic tool, especially in areas without advanced laboratory facilities. However, both tests were less accurate in patients who had recently taken antifungal or steroid medications.

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The impact of osteoarticular invasion by Coccidioides Sp disseminated infection

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A 48-year-old man from Mexico developed a serious fungal infection caused by Coccidioides, which spread from his lungs to his skin, bones, and joints, causing pain and swelling. Despite having a normally functioning immune system, he developed progressive disease that was initially misdiagnosed as rheumatoid arthritis. After switching to the antifungal medication fluconazole, his condition improved dramatically, with symptoms resolving within several months of treatment.

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New epidemiological routes of Coccidioidomycosis in Mexico – the extension of this pathogen to new areas

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Coccidioidomycosis, a fungal lung disease traditionally found in desert regions of Mexico and the southwestern United States, is spreading to new areas where it was never seen before. Researchers tracked 122 cases between 1991 and 2023 and found that nearly half of the patients had no history of travel to known high-risk areas, suggesting the disease is becoming established in new locations. Climate change and drought conditions are likely helping the fungus expand its range, making it important for doctors everywhere to consider this disease when diagnosing respiratory infections.

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Diagnostic performance of Aspergillus-specific immunoglobulin G immunochromatographic and enzyme-linked immunosorbent assay testing in chronic pulmonary aspergillosis: comparative analysis across subtypes and influencing factors

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Chronic pulmonary aspergillosis is a serious fungal lung infection that often develops after tuberculosis. This study compared two blood tests for diagnosing this disease: a quick point-of-care test and a traditional lab test. The quick test performed better overall and could be used in areas without advanced laboratory equipment, though previous antifungal or steroid medications can reduce its effectiveness.

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Fungi under fire: diagnostic capacities and antifungal availability in Peruvian healthcare facilities

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This study examined how well Peruvian hospitals can diagnose and treat serious fungal infections across the country. Researchers surveyed 54 healthcare centers and found that while basic fungal tests are available everywhere, advanced diagnostic tools and certain antifungal medications are mostly limited to the capital city of Lima. The research identifies major gaps in care that need to be addressed to help more patients survive these serious infections.

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Diagnostic performance of Aspergillus-specific immunoglobulin G immunochromatographic and enzyme-linked immunosorbent assay testing in chronic pulmonary aspergillosis: comparative analysis across subtypes and influencing factors

mycolabadmin

Chronic pulmonary aspergillosis (CPA) is a serious fungal lung infection that primarily affects people with existing lung conditions. This study compared two methods to detect the disease: a fast, portable test (ICT) and a traditional laboratory test (ELISA). The faster ICT test was more accurate overall and can provide results quickly in areas without advanced laboratory facilities. However, patients already taking antifungal medications had lower test accuracy with both methods.

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