secondary metabolites – Page 9

Trichoderma: The Current Status of Its Application in Agriculture for the Biocontrol of Fungal Phytopathogens and Stimulation of Plant Growth

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Trichoderma is a beneficial fungus that grows naturally in soil and can protect crops from harmful fungal diseases while promoting plant growth. It works through multiple mechanisms including directly attacking pathogenic fungi, competing for nutrients, and boosting the plant’s own defense systems. With over 77 commercial products already available, Trichoderma offers a promising sustainable alternative to chemical pesticides for protecting major world crops.

Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

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Morels are valuable mushrooms threatened by fungal wilt disease in China. Researchers isolated two beneficial bacteria (Streptomyces) from morel soil that naturally fight the fungal disease. When applied to morel fields, these bacteria reduced disease and increased mushroom yield by 30% compared to untreated fields. This represents a natural, eco-friendly solution to protect morel crops and boost production without chemical fungicides.

Xenorhabdus spp.: An Overview of the Useful Facets of Mutualistic Bacteria of Entomopathogenic Nematodes

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Xenorhabdus bacteria are tiny organisms that naturally live inside microscopic worms used for pest control. These bacteria produce powerful substances that can kill harmful insects, fungi, and plant-damaging worms without using toxic chemical pesticides. Scientists are discovering new types of these bacteria and their compounds, which could help create safer products for farming and disease control. This research shows these beneficial microbes could replace harmful chemicals in agriculture.

How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

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This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

Biocontrol of citrus fungal pathogens by lipopeptides produced by Bacillus velezensis TZ01

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Scientists discovered a beneficial bacterium called Bacillus velezensis that can protect citrus fruits from harmful fungi. This bacterium produces natural compounds called lipopeptides that kill disease-causing fungi without the need for chemical fungicides. The lipopeptides are stable and effective across different environmental conditions, making them promising for use in citrus farming as an eco-friendly alternative to traditional pesticides.

Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

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Researchers isolated eight new bioactive compounds from a rare European mushroom species called Hericium flagellum. These compounds showed promising ability to stimulate nerve cell growth and could potentially help treat neurodegenerative diseases like Alzheimer’s and Parkinson’s. The study demonstrates that mushroom-derived natural products may offer new therapeutic approaches for conditions affecting millions of elderly people worldwide.

Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites

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This study examined how different growing methods affect the medicinal compounds found in Taiwanofungus gaoligongensis, a rare Chinese medicinal fungus. Researchers discovered that growing this fungus on wood substrates from specific trees significantly increased production of beneficial compounds like antcins and antrodin C, which have anti-cancer and anti-inflammatory properties. By analyzing gene expression patterns, they identified key genes and regulatory mechanisms that control the production of these medicinal compounds, suggesting ways to improve cultivation methods for better medicinal value.

Interference with sexual mating of Sporisorium scitamineum by verrucarin A isolated from Paramyrothecium sp

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Scientists discovered a fungus called Paramyrothecium that produces a natural compound called verrucarin A, which stops sugarcane smut disease by preventing infected fungus cells from mating with each other. In greenhouse experiments, using this compound reduced disease symptoms from 80% infection down to 37%, and it didn’t harm the sugarcane plants. This provides a safe, natural way to control an important crop disease without using chemical pesticides.

Exo-metabolome profiling of soybean endophytes: a road map of antagonism against Fusarium oxysporum

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Scientists discovered that certain beneficial bacteria living inside soybean roots can protect the plant from a harmful fungus that causes root rot and reduces crop yield. By analyzing the chemical compounds these bacteria produce, researchers identified specific antifungal substances that kill or inhibit the pathogenic fungus. These findings suggest that instead of using harmful chemical fungicides, farmers could use these beneficial bacteria as a natural, environmentally-friendly way to protect soybean crops and improve agricultural sustainability.

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

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Cordyceps militaris is a medicinal fungus used in traditional medicine for treating fatigue, boosting immunity, and fighting cancer. This review explains how growing conditions—such as the type of grain or insect substrate used, light exposure, temperature, and nutrient balance—dramatically affect the production of beneficial compounds like cordycepin. The research shows that mixing grains with insect-based materials and using specific light wavelengths can significantly increase the potency of these medicinal fungi, making them more effective for health applications.

Research Keyword: secondary metabolites