Research Keyword: secondary metabolites

Actinomycetes isolated from rhizosphere of wild Coffea arabica L. showed strong biocontrol activities against coffee wilt disease

Researchers discovered that certain bacteria called actinomycetes, particularly a strain called MUA26, can effectively fight coffee wilt disease, a serious fungal infection that damages coffee plants. These beneficial bacteria produce natural compounds that kill the disease-causing fungus and were tested on coffee seedlings in a greenhouse, showing 83% effectiveness at preventing the disease. This discovery offers coffee farmers an organic alternative to chemical pesticides, which are expensive and harmful to the environment.

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Penicillium psychrofluorescens sp. nov., a naturally autofluorescent Antarctic fungus

Scientists discovered a new cold-loving fungus in Antarctic soil that glows remarkably bright under ultraviolet light. This fungus, named Penicillium psychrofluorescens, produces its own fluorescent chemicals and contains many genes for making novel medicinal compounds. Its unique characteristics suggest it could be valuable for developing new medicines and biotechnological applications.

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Complete genome sequence analysis of Boeremia exigua, a fungal pathogen causing leaf spot disease of Panax notoginseng

Scientists have sequenced the complete genome of Boeremia exigua, a fungus that causes leaf spot disease on Panax notoginseng (a valuable traditional Chinese medicinal plant). The study identified important genes related to how the fungus degrades plant cell walls, produces toxins, and causes disease. This genetic information will help researchers better understand how the pathogen works and develop more effective ways to protect the plants from infection.

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Bacterial–Fungal Interactions: Mutualism, Antagonism, and Competition

Bacteria and fungi in animal bodies interact in three main ways: they help each other (mutualism), fight each other (antagonism), or compete for resources. These interactions happen in the gut, rumen, and skin of animals. Understanding how to balance these relationships can help create better probiotics and natural alternatives to antibiotics for treating infections and improving animal health.

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Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

Morel mushrooms are delicious and nutritious but are threatened by a fungal disease that can destroy up to 80% of crops. Scientists discovered that two beneficial bacteria species (Streptomyces) from morel soil produce compounds that kill the disease-causing fungus. When applied to morel fields, these beneficial bacteria not only prevented the disease but also increased mushroom yields by about 30% compared to untreated crops, offering a natural and sustainable solution for morel farmers.

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Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals

This comprehensive review explores how compounds found in plants can protect our bodies from harmful damage caused by oxidative stress, which is linked to aging and various diseases. Plant-based foods rich in antioxidants like berries, leafy greens, and olive oil contain special molecules that can help prevent cancer, heart disease, diabetes, and other chronic conditions. The review highlights that these natural compounds work through multiple beneficial mechanisms beyond just antioxidant activity, making plant-based diets an effective strategy for maintaining health and preventing disease.

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The Efficacy of Clove Oil Against Aspergillus flavus and the Production of Aflatoxin B1 in Organic Peanuts in Georgia

Researchers tested clove essential oil as a natural antifungal treatment for peanuts infected with a mold that produces aflatoxin, a dangerous toxin harmful to human health. They found that clove oil significantly reduced both the mold growth and toxin production, with the best results at moderate concentrations. This discovery offers organic farmers an eco-friendly alternative to synthetic fungicides for protecting their peanut crops. The findings could help reduce a major agricultural problem that costs the Southeast millions of dollars annually.

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Volatile Organic Compounds Produced by Co-Culture of Burkholderia vietnamiensis B418 with Trichoderma harzianum T11-W Exhibits Improved Antagonistic Activities against Fungal Phytopathogens

Scientists studied how two beneficial microorganisms (a bacterium and a fungus) work together to produce compounds that kill plant-damaging fungi. When grown together, they produced more protective compounds than when grown separately, showing promise as a natural alternative to chemical fungicides for protecting crops and stored fruits from fungal diseases.

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Antifungal Activity of Industrial Bacillus Strains against Mycogone perniciosa, the Causative Agent of Wet Bubble Disease in White Button Mushrooms

Researchers tested two special bacteria strains (Bacillus subtilis B-10 and M-22) to protect white button mushrooms from wet bubble disease, a serious fungal infection that can destroy entire crops. When applied to mushroom growing beds, both bacteria effectively prevented the disease-causing fungus from developing, with success rates between 50-99% depending on application method. This offers mushroom farmers a natural, chemical-free alternative to synthetic fungicides for protecting their crops.

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Soil microorganism colonization influenced the growth and secondary metabolite accumulation of Bletilla striata (Thunb.) Rchb. F.

Chinese ground orchid (Bletilla striata) is a medicinal plant whose growth and medicinal compound production depend heavily on soil microorganisms. Researchers found that different soil types harbor different beneficial microbes: sandy loam soils boost plant growth, while sandy clay soils increase medicinal compound concentration. Specific microbes colonize different plant parts, with some promoting growth in roots and tubers, while others enhance the production of militarine, a compound with potential anti-aging and cognitive benefits.

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