secondary metabolites – Page 3

A comprehensive review of mycotoxins, their toxicity, and innovative detoxification methods

mycolabadmin

Mycotoxins are poisons produced by molds that commonly contaminate foods like grains, nuts, and spices, causing serious health problems in people and animals. This comprehensive review examines how these toxins affect our health, how to detect them in food, and various methods to remove or destroy them. Traditional approaches using biological agents and chemicals work well but are only partially effective, while newer innovative methods using nanoparticles and plant extracts show greater promise for more complete protection of our food supply.

Genomic Insights into the Microbial Agent Streptomyces albidoflavus MGMM6 for Various Biotechnology Applications

mycolabadmin

Scientists analyzed the genetic makeup of a soil bacterium called Streptomyces albidoflavus MGMM6 and discovered it has remarkable abilities for cleaning up pollution. The bacterium can break down harmful dyes used in industries, remove heavy metals from wastewater, and kill plant disease-causing fungi. These findings suggest this microorganism could be used in agriculture to protect crops and in environmental cleanup efforts.

Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

mycolabadmin

Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

Novel Antimicrobial Activities of Albofungin, Albonoursin, and Ribonucleosides Produced by Streptomyces sp. Caat 5-35 Against Phytopathogens and Their Potential as a Biocontrol Agent

mycolabadmin

Scientists discovered that a soil bacterium called Streptomyces sp. Caat 5-35 produces natural compounds that can kill crop-damaging pathogens. These compounds, including albofungin and albonoursin, showed strong activity against diseases affecting cacao and palm crops. The bacterium also helps plants by breaking down cellulose and making phosphorus more available, making it a promising tool for natural crop protection without synthetic chemicals.

The Application of Fungi and Their Secondary Metabolites in Aquaculture

mycolabadmin

Fungi can help solve several problems in fish farming. They can make plant-based fish feed more nutritious and easier to digest, boost fish immune systems and disease resistance without antibiotics, help fish feed float better in water, and clean up polluted water from fish farms. This makes aquaculture more sustainable and environmentally friendly while reducing costs for farmers.

Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

mycolabadmin

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively prevent the production of aflatoxin B1, a highly toxic and cancer-causing substance produced by certain molds that contaminate crops like corn and wheat. The mushroom extracts work by inhibiting the toxin production by up to 94%, offering a natural, environmentally-friendly alternative to chemical pesticides. The study suggests that compounds in mushrooms, including special sugars and enzymes, may help protect food supplies from this dangerous contamination, which is becoming increasingly important as climate change creates more favorable conditions for mold growth.

Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids

mycolabadmin

Scientists analyzed 226 mushroom samples from about 30 psychotropic species to measure their psilocybin and related compound content. They found that the amounts of these compounds vary greatly, even within the same species, making it difficult to predict how strong a mushroom will be. The research shows that Psilocybe species generally contain the most psychoactive compounds, with some varieties containing over 15 times more psilocybin than others, highlighting safety concerns for users.

Synergistic curative effects of Trichoderma hamatum and Rumex dentatus against Alternaria alternata, the causal agent of tomato leaf spot disease

mycolabadmin

This research discovered that combining a beneficial fungus called Trichoderma hamatum with an extract from Rumex dentatus plant effectively controls tomato leaf spot disease. When used together, these natural treatments reduced disease by over 88% and even outperformed commercial fungicides. The combined treatment also boosted plant health by increasing growth and natural defense mechanisms, offering farmers an affordable and environmentally safe alternative to chemical pesticides.

The treasured giants: a current overview on agricultural, nutritional, bioactive, and economic potential of Macrocybe Species (Agaricales, Basidiomycota)

mycolabadmin

Macrocybe mushrooms are giant edible fungi found in tropical regions worldwide that offer significant nutritional and health benefits. These mushrooms can be cultivated using agricultural waste materials like sawdust and straw, making them an economical crop. Rich in proteins, fibers, vitamins, and medicinal compounds, they possess antimicrobial and immune-boosting properties that could benefit human health.

Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus

mycolabadmin

Researchers successfully revived a beneficial fungus called Acremonium sp. MEP2000 that had lost its effectiveness through repeated cultivation by adding birch bark powder and medicinal mushroom powder to its growth medium. When used to treat the medicinal fungus Inonotus obliquus (chaga), this revitalized fungal culture dramatically improved the growth and production of healthy bioactive compounds like polysaccharides and triterpenoids. This breakthrough offers a practical solution for large-scale production of medicinal fungi with enhanced therapeutic potential for treating cancer, diabetes, and inflammatory conditions.

Research Keyword: secondary metabolites