secondary metabolites – Page 18

Antimicrobial and Antifungal Activities of Proline-Based 2,5-Diketopiperazines Occurring in Food and Beverages and Their Synergism with Lactic Acid

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Researchers synthesized special cyclic peptides called 2,5-diketopiperazines (found naturally in fermented foods like bread and cheese) and tested their ability to kill harmful molds and bacteria. When combined with lactic acid (a natural preservative), these compounds worked extremely well together, achieving nearly complete mold inhibition. This research suggests that using special starter cultures that naturally produce these compounds could help keep food fresh longer without artificial preservatives.

Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review

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Ganoderma neo-japonicum, known as purple Lingzhi, is a mushroom traditionally used by indigenous communities in Malaysia and other Asian countries to treat various health conditions. This review examines 36 scientific studies published between 1991 and 2021, showing that the mushroom contains special compounds that can fight cancer cells, lower blood sugar, reduce inflammation, and boost immunity. While laboratory studies show promising results, the mushroom still needs more clinical testing in humans before it can be widely used as a medicine.

A New Species and Five New Records of Talaromyces (Eurotiales, Aspergillaceae) Belonging to Section Talaromyces in Korea

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Researchers surveying fungal diversity in Korea discovered one new species of Talaromyces fungus and confirmed five additional species previously unknown to the country. These fungi were isolated from soil, freshwater, and indoor air samples and identified using genetic analysis and visual characteristics. Many species in this fungal genus produce valuable compounds with potential medical and agricultural applications, making them important for biotechnology research.

Different metabolite profiles across Penicillium roqueforti populations associated with ecological niche specialisation and domestication

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This study examined how different populations of the blue cheese fungus Penicillium roqueforti produce varying amounts of toxic and beneficial compounds depending on their environment. Cheese-making strains were found to produce fewer toxins than strains from spoiled food and lumber, likely due to selective breeding for safer products. The research identified specific genetic mutations that prevent cheese strains from producing certain toxins, helping explain why some cheese strains are safer than others.

Genome Sequencing of Cladobotryum protrusum Provides Insights into the Evolution and Pathogenic Mechanisms of the Cobweb Disease Pathogen on Cultivated Mushroom

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Researchers sequenced the complete genome of Cladobotryum protrusum, a fungus that causes cobweb disease on cultivated mushrooms. This genome contains genes for producing toxins and enzymes that help the fungus attack and digest mushroom cells. Understanding this genetic blueprint could help farmers develop better strategies to control this disease and protect their mushroom crops from significant economic losses.

Aokap9 gene knockout contributes to kojic acid synthesis in Aspergillus oryzae

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Researchers discovered that removing the Aokap9 gene in the fungus Aspergillus oryzae doubles the production of kojic acid, a valuable chemical used in skin-whitening cosmetics and food preservation. By combining the Aokap9 gene removal with modifications to other genes (kojR and AozfA), they achieved even higher production levels. This research provides a practical pathway for creating high-yield strains that can produce kojic acid more efficiently for commercial applications.

Antagonistic potential and analytical profiling of plant probiotic bacteria using chromatography and mass spectrometry techniques against Botrytis cinerea and Fusarium oxysporum

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Researchers discovered that certain beneficial bacteria can fight plant diseases caused by harmful fungi. Two bacteria strains showed exceptional ability to inhibit the growth of disease-causing fungi that damage crops. These bacteria produce natural compounds like phenols and organic acids that help plants grow better and resist diseases. This research suggests these bacteria could be used as natural alternatives to chemical pesticides for sustainable farming.

Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh

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Researchers discovered several types of fungi living inside seaweed from Bangladesh’s Bay of Bengal coast. These fungi produce natural compounds that can fight bacteria, reduce harmful oxidative damage, and potentially kill cancer cells. The study identified specific chemical compounds responsible for these beneficial properties, suggesting these fungi could be useful sources for developing new medicines.

Identification, characterization, antimicrobial activity and biocontrol potential of four endophytic fungi isolated from Amazonian plants

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Scientists isolated four types of fungi living inside the leaves of medicinal plants from the Amazon region of Bolivia. These fungi produce natural compounds that kill harmful bacteria and fungi that damage potato crops. The findings show promise for developing natural alternatives to synthetic pesticides and antibiotics for agricultural and medical applications.

Identification and growth-promoting effect of Paecilomyces lilacinus a biocontrol fungi for walnut rot disease

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Researchers identified a beneficial fungus called Paecilomyces lilacinus that can fight walnut rot disease, which damages walnut crops especially in China’s Xinjiang region. This fungus is more environmentally friendly than chemical fungicides and actually boosts walnut plant growth, increasing seedling height and root development significantly. The study shows it could replace harmful chemical treatments while improving overall plant health.

Research Keyword: secondary metabolites