secondary metabolites – Page 14

Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

mycolabadmin

Scientists discovered a beneficial fungus living inside the leaves of an Iranian medicinal plant. They isolated three compounds from this fungus, with the main compound showing powerful activity against drug-resistant bacteria and plant-damaging fungi. This discovery suggests that beneficial fungi within plants could be valuable sources for developing new medicines and natural pesticides.

Fungal-fungal cocultivation alters secondary metabolites of marine fungi mediated by reactive oxygen species (ROS)

mycolabadmin

Researchers discovered that when two types of ocean fungi grow together, one of them produces a protective chemical called alternariol that can kill bacteria and cancer cells. This happens because the fungi recognize each other as competitors and trigger special stress signals that activate defensive chemical production. Interestingly, fungi from the ocean respond differently than those from land, suggesting they have evolved unique survival strategies for harsh marine environments.

Biodiversity-Driven Natural Products and Bioactive Metabolites

mycolabadmin

This comprehensive review explores how diverse organisms like plants, fungi, and marine creatures produce remarkable chemical compounds for survival and defense. These natural products have inspired many modern medicines, but scientists now understand that the chemical diversity comes not just from the organisms themselves but from their ecological interactions and environmental challenges. By studying how these chemicals are made and what triggers their production, researchers can discover new drugs and medicines while protecting the ecosystems that generate them.

In vitro and In silico investigation deciphering novel antifungal activity of endophyte Bacillus velezensis CBMB205 against Fusarium oxysporum

mycolabadmin

Researchers isolated a beneficial bacteria called Bacillus velezensis from medicinal plants that can fight against a dangerous fungus causing banana wilt disease. Through laboratory and computer studies, they identified two natural compounds produced by this bacteria that stop the fungus from growing by damaging its cell walls. This discovery offers a promising eco-friendly alternative to chemical fungicides for protecting banana crops worldwide.

Unveiling the hidden arsenal: exploring secondary metabolites and fungal development in pathogenic fungi

mycolabadmin

Dangerous fungi produce hidden chemical compounds that help them infect humans and crops while also potentially serving as medicines. Scientists are studying how these compounds work and how fungi make them to develop better treatments and protect our food supply. This editorial highlights recent research showing that understanding fungal chemistry from genetic, ecological, and medical perspectives will help us fight fungal diseases as resistance increases.

Marine Fungal Metabolites: A Promising Source for Antibiofilm Compounds

mycolabadmin

Bacteria can form protective layers called biofilms that resist antibiotics, causing serious infections. Scientists are discovering that fungi living in seaweed and marine environments produce natural compounds that can break down these biofilm barriers. This review shows that marine fungi offer promising new alternatives to combat antibiotic-resistant infections, though more research is needed to fully explore their potential.

Beauveria felina Accelerates Growth When Competing With Other Potential Endophytes

mycolabadmin

Scientists studied how Beauveria felina, a fungus used to fight crop pests, grows when competing with other fungi naturally found in plants. Surprisingly, B. felina grew faster when other fungi were present, making it an even stronger candidate for pest control. However, the researchers found complex interactions between the fungi that need more study before using B. felina widely in agriculture.

Three new species of Talaromyces sect. Talaromyces discovered in China

mycolabadmin

Scientists discovered three previously unknown species of Talaromyces fungi in soil samples from China. These fungi were identified by examining their physical appearance under microscopes and analyzing their genetic material. Each new species has unique characteristics and belongs to different groups within the Talaromyces genus. These discoveries add to our understanding of fungal diversity and highlight the importance of studying these organisms that can be valuable for producing enzymes and medicines.

Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

mycolabadmin

Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

Influences of substrate and tissue type on erinacine production and biosynthetic gene expression in Hericium erinaceus

mycolabadmin

This study examined how different growing conditions and tissue types affect erinacine production in lion’s mane mushrooms. Researchers found that mycelium (the fungal threads) produced far more erinacines than fruit bodies, and that the type of growth medium significantly influenced which erinacines were produced. Interestingly, changes in erinacine production weren’t always reflected in gene activity levels, suggesting other cellular mechanisms control these beneficial compounds.

Research Keyword: secondary metabolites