Research Keyword: Schizophyllum commune

Traumatic implantation keratitis caused by Schizophyllum commune in Central India

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This report describes two patients in India who developed serious fungal eye infections (keratitis) after corneal injuries. The infection was caused by Schizophyllum commune, a mushroom-like fungus found on decaying wood. Despite aggressive treatment with antifungal medications and surgery, both patients lost vision in their affected eyes. The case highlights how difficult it is to identify and treat this rare fungus.

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Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab

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A 70-year-old man developed a serious lung condition caused by a fungal infection (Schizophyllum commune) that resulted in dangerous mucus buildup and asthma attacks despite standard treatments. When traditional medications failed, doctors tried a newer biologic drug called mepolizumab that targets immune cells causing inflammation. The treatment successfully cleared the mucus, improved breathing, and allowed the patient to stop taking steroid medications while remaining symptom-free for over two years.

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Morphological and molecular identification of Schizophyllum commune causing storage bulb rot disease of Lanzhou edible lily in China and its biological characteristics

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Researchers in China identified Schizophyllum commune as a fungal pathogen causing rot in stored edible lily bulbs, marking the first report of this disease. The fungus was identified using microscopic examination and genetic sequencing, and was shown to cause 100% infection on lily bulbs. The study found that the fungus grows best at 30°C with high humidity and darkness, providing important information for controlling this storage disease that causes significant crop losses.

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Schizophyllum commune infection following chimeric antigen receptor T-cell therapy in a patient with lymphoma

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A 71-year-old woman receiving CAR T-cell therapy for lymphoma developed a rare fungal lung infection caused by Schizophyllum commune six months after treatment. The infection presented similarly to other fungal diseases affecting the lungs and was diagnosed through bronchoscopy and fungal culture despite negative blood antibody tests. Standard antifungal medication (voriconazole) taken by mouth for four months completely resolved the infection, highlighting the need to consider rare fungi in patients receiving advanced cancer immunotherapies.

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The Role of Nitric Oxide in the Growth and Development of Schizophyllum commune Under Anaerobic Conditions

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This study shows that nitric oxide, a chemical messenger, plays an important role in helping a wood-decay fungus called Schizophyllum commune grow and reproduce in environments without oxygen. When nitric oxide levels are boosted, the fungus grows better and can even start forming fruiting bodies (mushrooms) under low-oxygen conditions. These findings could help scientists understand how fungi survive and thrive in extreme environments like deep ocean sediments.

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Schizophyllum commune

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Schizophyllum commune, commonly known as the split-gill mushroom, is a fungus that grows on wood and was historically considered just a common environmental organism. However, scientists discovered in 1950 that this mushroom could actually infect human tissue, causing conditions like nail infections. This discovery was surprising because mushrooms were not previously known to infect living animals. Today, researchers recognize it as an emerging fungal pathogen that can pose health risks to humans.

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