SCFA production – mycolab.ai

How Do Cyclodextrins and Dextrans Affect the Gut Microbiome? Review of Prebiotic Activity

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Cyclodextrins and dextrans are substances commonly used in medicines that may have unexpected health benefits for your gut bacteria. Research shows these compounds can help beneficial bacteria like Lactobacillus and Bifidobacterium grow better in your digestive system. When these good bacteria ferment these substances, they produce helpful compounds called short-chain fatty acids that improve overall gut health and may help with conditions like obesity and inflammation.

Gut-Brain Axis in Obesity: How Dietary Patterns Influence Psychological Well-Being and Metabolic Health

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This review explains how our diet affects both our gut bacteria and our mental health through the gut-brain axis, a communication system between our digestive system and brain. Mediterranean diets rich in fiber and healthy foods support beneficial bacteria and mental well-being, while Western diets high in processed foods harm gut health and increase obesity risk. Emotional eating driven by stress and depression worsens obesity, but targeted dietary interventions with prebiotics, probiotics, and fiber can help restore balance and improve both physical and mental health.

Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne

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This study tested two supplements for treating non-cystic acne: one containing probiotics and herbs, and another based on myoinositol and medicinal plants. Both supplements significantly reduced acne lesions and improved gut health by increasing beneficial bacteria and beneficial fatty acids produced by these bacteria. The myoinositol-based supplement also reduced hormone precursors related to acne development. These findings suggest that supporting gut health may be an effective way to treat acne.

Galacto-Oligosaccharides Exert Bifidogenic Effects at Capsule-Compatible Ultra-Low Doses

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This study tested whether tiny doses of a prebiotic called galacto-oligosaccharides (GOS) could be effective when taken in capsule form instead of large sachets. Researchers used a specially designed laboratory system to simulate how these compounds work in the human gut. Even at the lowest dose tested (0.5 g), the GOS successfully increased beneficial gut bacteria and produced helpful compounds that support digestive health, while producing minimal gas.

Prebiotic and Functional Fibers from Micro- and Macroalgae: Gut Microbiota Modulation, Health Benefits, and Food Applications

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Seaweed and other algae contain special fibers called polysaccharides that act like fertilizer for beneficial bacteria in your gut. When these good bacteria ferment these algal fibers, they produce substances called short-chain fatty acids that support digestive health, boost immunity, and help control blood sugar and weight. These algae-based fibers are sustainable alternatives to synthetic prebiotics and can be added to foods and supplements.

Triacetin and a Mushroom Blend Restore Butyrate Production by IBS Microbiomes Ex Vivo, Thus Promoting Barrier Integrity

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Researchers tested two natural products—triacetin and a mushroom blend—to see if they could help people with IBS by improving their gut bacteria and strengthening their intestinal lining. Both products successfully increased beneficial short-chain fatty acids and improved barrier integrity, with triacetin having the added advantage of producing less uncomfortable gas. These findings suggest these products could offer a new dietary approach to managing IBS symptoms.

Effects of fiber sources with different solubilities on the growth performance, nutrient metabolism, antioxidant, immune capacity and intestinal health of meat geese

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This study examined how different types of dietary fiber affect the health and growth of meat geese. Researchers compared three fiber sources with different levels of solubility: wheat bran (highly soluble), alfalfa meal (moderately soluble), and bamboo meal (low solubility). They found that the highly soluble fiber source improved growth, enhanced immune and antioxidant functions in the intestines, and promoted beneficial bacteria, making it the best choice for geese farming.

Bioactive Peptides from Quinoa (Chenopodium quinoa Willd.) as Modulators of the Gut Microbiome: A Scoping Review of Preclinical Evidence

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This review examines how quinoa and its protein-derived peptides can improve gut health by changing the balance of bacteria in the digestive system. Research shows that quinoa helps boost beneficial bacteria, increases diversity of microbial communities, and promotes production of butyrate, a beneficial compound that supports intestinal health. Different disease conditions show specific improvements, such as reduced harmful bacteria in colitis and better metabolic balance in obesity, suggesting quinoa could be tailored for personalized health interventions.

A novel synbiotic formulation prevents calcium oxalate stones by restoring gut microbiota homeostasis

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This study tested a special probiotic and prebiotic combination to prevent kidney stones caused by too much oxalate in the body. The formula containing three beneficial bacteria strains and a plant-based fiber worked better than any single component alone. The treatment restored healthy gut bacteria, protected the intestinal lining, and reduced the amount of oxalate reaching the kidneys, effectively preventing stone formation in animal models.

Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

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This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

Research Keyword: SCFA production